PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1805447-0	1991	Inhibitory effect of heparin cofactor II on thrombin-stimulated prostacyclin production by cultured vascular smooth muscle cells.	Epoprostenol	64-76	serine (or cysteine) peptidase inhibitor, clade D, member 1	Mus musculus	21-40	
1805447-1	1991	We investigated the effect of heparin cofactor II (HCII) on thrombin-induced prostacyclin (PGI2) production by A10 cells, an established cell line of vascular smooth muscle cells from murine aorta.	Epoprostenol	77-89	serine (or cysteine) peptidase inhibitor, clade D, member 1	Mus musculus	51-55	
1805447-4	1991	However, when A10 cells were preincubated with HCII for 30 min before exposure to thrombin, the PGI2 production was markedly inhibited.	Epoprostenol	96-100	serine (or cysteine) peptidase inhibitor, clade D, member 1	Mus musculus	47-51	
1805447-7	1991	From these results, it was suggested that HCII would be activated by glycosaminoglycans (GAGs) such as dermatan sulfate of the cell layers and could inhibit thrombin-induced PGI2 production.	Epoprostenol	174-178	serine (or cysteine) peptidase inhibitor, clade D, member 1	Mus musculus	42-46