PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22158046-6 2012 IL-6/PAI-1 expression and secretion were strongly inhibited by the tyrosine kinase inhibitor AG1478 and EGFR silencing. RTKI cpd 93-99 interleukin 6 Homo sapiens 0-4 21868713-7 2012 HN2-related effects on the secretion of IL-6 and the production of total mucin and MUC5AC were reversed by the selective EGFR inhibitor AG1478 and by an EGFR-blocking antibody. RTKI cpd 136-142 interleukin 6 Homo sapiens 40-44 20184800-9 2010 Moreover, AG-1478 (2 microM), reduced BK-induced IL-6 secretion by 28% and abrogated the synergic induction of IL-6 induced by BK plus EGF (from 8312 +/- 1267 to 3229 +/- 597 pg/ml, n = 5, p < 0.05). RTKI cpd 10-17 interleukin 6 Homo sapiens 49-53 20739465-10 2011 Hypertonicity-induced increases in IL-6 and IL-8 releases were suppressed by exposure to capsazepine, AG 1478, ERK inhibitor PD 98059, p38 inhibitor SB 203580, or NF-kappaB inhibitor PDTC. RTKI cpd 102-109 interleukin 6 Homo sapiens 35-39 20184800-9 2010 Moreover, AG-1478 (2 microM), reduced BK-induced IL-6 secretion by 28% and abrogated the synergic induction of IL-6 induced by BK plus EGF (from 8312 +/- 1267 to 3229 +/- 597 pg/ml, n = 5, p < 0.05). RTKI cpd 10-17 interleukin 6 Homo sapiens 111-115 20184800-10 2010 AG-1478 dual effects on IL-6 secretion induced by BK alone or BK plus EGF were also observed in cells treated with genistein, a tyrosine kinase inhibitor, and AG-825, an ErbB-2 inhibitor. RTKI cpd 0-7 interleukin 6 Homo sapiens 24-28 17130674-7 2006 However, AG1478, an epidermal growth factor (EGF)-receptor inhibitor, partially decreased UTP-induced ERK phosphorylation and IL-6 expression. RTKI cpd 9-15 interleukin 6 Homo sapiens 126-130