PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11907276-5	2002	Surprisingly, whereas the caspase inhibitor zVAD prevented CD95-mediated apoptosis, it potentiated TNF-induced necrosis.	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	44-48	Fas (TNF receptor superfamily member 6)	Mus musculus	59-63	
11035073-4	2000	This process was preceded by up-regulation of Fas (CD95) and Fas ligand expression in response to IL-12 plus IL-18 and was blocked by zVAD, a large spectrum caspase inhibitor, as well as by anti-Fas ligand mAb, suggesting the involvement of the Fas pathway.	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	134-138	Fas (TNF receptor superfamily member 6)	Mus musculus	51-55	
10827087-8	2000	A similar, but weaker sensitization of zVAD.fmk to treatment with the TNF-related apoptosis-inducing ligand (TRAIL) or anti-CD95 antibody was demonstrated.	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	39-43	Fas (TNF receptor superfamily member 6)	Mus musculus	124-128	
10606248-4	1999	However, zVAD-fmk was efficacious in inhibiting cell death triggered by an activating anti-Fas/CD95 antibody.	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	9-17	Fas (TNF receptor superfamily member 6)	Mus musculus	95-99	
9093874-3	1997	Mice pretreated with the inhibitor, Z-VAD-fluoromethylketone (FMK) were dose-dependently protected from liver injury caused by CD95 activation as determined by plasma alanine aminotransferase and also from hepatocyte apoptosis assessed by DNA fragmentation (ID50 = 0.1 mg/kg).	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	36-60	Fas (TNF receptor superfamily member 6)	Mus musculus	127-131	
9093874-3	1997	Mice pretreated with the inhibitor, Z-VAD-fluoromethylketone (FMK) were dose-dependently protected from liver injury caused by CD95 activation as determined by plasma alanine aminotransferase and also from hepatocyte apoptosis assessed by DNA fragmentation (ID50 = 0.1 mg/kg).	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	62-65	Fas (TNF receptor superfamily member 6)	Mus musculus	127-131