PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23162658-10	2012	The caspase inhibitor Z-VAD-FMK and the STAT3 inhibitor blocked this IFNgamma-induced apoptosis.	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	22-31	interferon gamma	Homo sapiens	69-77	
10759183-6	2000	Furthermore, IFN-gamma-treated OLs became susceptible to Fas-mediated apoptosis when compared with untreated cells, and were protected by pretreatment with the caspase inhibitor ZVAD.	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	178-182	interferon gamma	Homo sapiens	13-22	
15547726-6	2004	IFN-gamma-mediated facilitation of apoptosis was inhibited by the pan-caspase inhibitor zVAD-fmk and the caspase-8 specific inhibitor zIEDT-fmk, indicating an important role of caspase-8 in mediating sensitation by IFN-gamma in neuroblastoma cells.	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	88-96	interferon gamma	Homo sapiens	0-9	
15547726-6	2004	IFN-gamma-mediated facilitation of apoptosis was inhibited by the pan-caspase inhibitor zVAD-fmk and the caspase-8 specific inhibitor zIEDT-fmk, indicating an important role of caspase-8 in mediating sensitation by IFN-gamma in neuroblastoma cells.	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	88-96	interferon gamma	Homo sapiens	215-224	
12368221-6	2002	Treatment of CD95L-transduced cells with IFN-gamma causes apoptosis within 24 to 36 hours that can be blocked by antagonistic anti-CD95 antibody or by the caspase-inhibitory peptide zVAD-FMK.	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	182-190	interferon gamma	Homo sapiens	41-50	
11454803-10	2001	Furthermore, the caspase inhibitor z-vad-fmk completely prevented IFN-gamma mediated apoptosis.	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	35-44	interferon gamma	Homo sapiens	66-75	
31217278-7	2019	In human colorectal adenocarcinoma-derived HT29 cells, PS exposure and necroptosis were similarly induced by treatment with IFN-gamma in the presence of Smac mimetics and z-VAD-fmk.	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	171-180	interferon gamma	Homo sapiens	124-133	
9271410-10	1997	Moreover, both EGF-induced apoptosis and IFN-gamma-induced apoptosis were effectively blocked by Z-Val-Ala-Asp-fluoromethylketone (ZVAD) in all the cells tested, and studies from ICE-deficient cells indicated that ICE gene expression was necessary for IFN-gamma-induced apoptosis.	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	97-129	interferon gamma	Homo sapiens	41-50	
9271410-10	1997	Moreover, both EGF-induced apoptosis and IFN-gamma-induced apoptosis were effectively blocked by Z-Val-Ala-Asp-fluoromethylketone (ZVAD) in all the cells tested, and studies from ICE-deficient cells indicated that ICE gene expression was necessary for IFN-gamma-induced apoptosis.	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	97-129	interferon gamma	Homo sapiens	252-261	
9271410-10	1997	Moreover, both EGF-induced apoptosis and IFN-gamma-induced apoptosis were effectively blocked by Z-Val-Ala-Asp-fluoromethylketone (ZVAD) in all the cells tested, and studies from ICE-deficient cells indicated that ICE gene expression was necessary for IFN-gamma-induced apoptosis.	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	131-135	interferon gamma	Homo sapiens	41-50	
9271410-10	1997	Moreover, both EGF-induced apoptosis and IFN-gamma-induced apoptosis were effectively blocked by Z-Val-Ala-Asp-fluoromethylketone (ZVAD) in all the cells tested, and studies from ICE-deficient cells indicated that ICE gene expression was necessary for IFN-gamma-induced apoptosis.	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	131-135	interferon gamma	Homo sapiens	252-261