PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9593265-4	1998	The induced PARP cleavage activities were blocked by the caspase inhibitors z-DEVD-fluoromethyl ketone (z-DEVD-FMK) and z-VAD-fluoromethyl ketone (z-VAD-FMK), or by overexpression in 32D cells of Bcl-2 or BCR/ABL.	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	120-145	B cell leukemia/lymphoma 2	Mus musculus	196-201	
22971741-3	2012	We found that TNFalpha- or zVAD-induced necroptosis occurs independently of the recently implicated executioners Bmf or PARP-2, but can involve the Bcl-2 family proteins Bid and Bak.	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	27-31	B cell leukemia/lymphoma 2	Mus musculus	148-153	
17873911-10	2008	Death of BIK-expressing Bcl-2-/- cells treated with zVAD-fmk was increased under caspase-8 depletion.	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	52-60	B cell leukemia/lymphoma 2	Mus musculus	24-29	
17304106-3	2007	Treatment of the mice with z-VAD-fmk, a potent broad specific caspase inhibitor, significantly reduced the degree of (1) spinal cord inflammation and tissue injury (histological score), (2) neutrophil infiltration (myeloperoxidase activity), (3) nitrotyrosine formation, and (4) apoptosis (TUNEL staining and Bax and Bcl-2 expression).	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	27-36	B cell leukemia/lymphoma 2	Mus musculus	317-322	
10373464-5	1999	Consistent with Bcl-2 cleavage being a caspase-mediated event, this cleavage is inhibitable by 50 microM CBZ-Val-Ala-Asp-fluoromethylketone (zVAD-fmk).	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	141-149	B cell leukemia/lymphoma 2	Mus musculus	16-21	
10373464-6	1999	Furthermore, Bcl-2 can cooperate with the caspase inhibitor zVAD-fmk in a dose-dependent manner to block TNFalpha-induced cell death.	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	60-68	B cell leukemia/lymphoma 2	Mus musculus	13-18	
10373464-7	1999	Overexpression of Bcl-2 results in a 10-fold decrease in the amount of zVAD-fmk required to inhibit TNFalpha-induced apoptosis.	benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone	71-79	B cell leukemia/lymphoma 2	Mus musculus	18-23