PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11755144-5 2001 The caspase inhibitor, Z-Val-Ala-Asp-fluoromethylketone (Z-VAD-fmk), resulted in a dose-dependent inhibition of apoptosis and beta-catenin cleavage. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone 23-55 catenin beta 1 Homo sapiens 126-138 15567157-5 2005 The caspase inhibitor ZVAD blocked beta-catenin cleavage by p-NO-ASA and partially reversed cell growth inhibition by p-NO-ASA but not that by ASA. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone 22-26 catenin beta 1 Homo sapiens 35-47 15067380-6 2004 The cleavage of beta-catenin was inhibited by the caspase inhibitors Z-VAD-fmk and Z-DEVD-fmk. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone 69-78 catenin beta 1 Homo sapiens 16-28 14555707-8 2003 Pretreatment with the caspase inhibitor z-VAD-fmk blocked morphological signs of apoptosis as well as caspase cleavage, and also partially prevented beta-catenin degradation by sulindac metabolites. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone 40-49 catenin beta 1 Homo sapiens 149-161 17030184-6 2006 GTN-induced beta-catenin degradation involves proteases that are sensitive to a broad-spectrum caspase inhibitor, z-VAD-fmk, and to serine protease inhibitors N-tosyl-L-phenylalaline chloromethyl ketone (TPCK) and [4-(2-aminoethyl)-benzenesulfonylfluoride] (AEBSF), whereas the ubiquitin/proteasome pathway is not involved. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone 114-123 catenin beta 1 Homo sapiens 12-24 11755144-5 2001 The caspase inhibitor, Z-Val-Ala-Asp-fluoromethylketone (Z-VAD-fmk), resulted in a dose-dependent inhibition of apoptosis and beta-catenin cleavage. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone 57-66 catenin beta 1 Homo sapiens 126-138 11179455-9 2001 Furthermore, paclitaxel-induced apoptosis and cleavage of beta-catenin and gamma-catenin were inhibited by the pan-caspase inhibitor Z-VAD-FMK and partially inhibited by the caspase-3 inhibitor Z-DEVD-FMK but were not affected by the caspase-1 inhibitor AC-YVAD-CMK. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone 133-142 catenin beta 1 Homo sapiens 58-70