PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22166213-5	2012	Under AUR1-repressive conditions, SCS7 and SUR2 mutants showed reductions in the complex sphingolipid levels and the accumulation of ceramide, like wild-type cells.	Ceramides	133-141	sphingosine hydroxylase	Saccharomyces cerevisiae S288C	43-47	
12006573-7	2002	Gene dosage experiments using the sphingolipid long chain sphingoid base (LCB) hydroxylase gene, SUR2, suggest that erg26-1 cells may accumulate LCB, thus placing one point of sterol regulation of sphingolipid synthesis possibly at the level of ceramide metabolism.	Ceramides	245-253	sphingosine hydroxylase	Saccharomyces cerevisiae S288C	97-101	
9368039-0	1997	Hydroxylation of Saccharomyces cerevisiae ceramides requires Sur2p and Scs7p.	Ceramides	42-51	sphingosine hydroxylase	Saccharomyces cerevisiae S288C	61-66	
9368039-2	1997	Sur2p is required for the hydroxylation of C-4 of the sphingoid moiety of ceramide, and Scs7p is required for the hydroxylation of the very long chain fatty acid.	Ceramides	74-82	sphingosine hydroxylase	Saccharomyces cerevisiae S288C	0-5	
26404656-5	2015	Loss of MIPC synthesis or an increase in the hydroxylation level of the ceramide moiety of sphingolipids on overexpression of Scs7 and Sur2 sphingolipid hydroxylases enhanced the growth defect of V-ATPase-deleted cells at pH 7.2.	Ceramides	72-80	sphingosine hydroxylase	Saccharomyces cerevisiae S288C	135-139	
20208441-6	2010	In this study, we investigated the effect of the genes involved in the synthesis of ceramide, lcb1, lcb2, tsc10, lac1, lag1, and sur2 on ceramide production levels.	Ceramides	137-145	sphingosine hydroxylase	Saccharomyces cerevisiae S288C	129-133	
9368039-5	1997	Characterization of scs7 and sur2 mutants is expected to provide insight into the function of ceramide hydroxylation.	Ceramides	94-102	sphingosine hydroxylase	Saccharomyces cerevisiae S288C	29-33