PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12074575-1 2002 We have demonstrated previously that IGFBP-5 alone had no effect on cell death but modulated ceramide-induced apoptosis in Hs578T IGF non-responsive cells. Ceramides 93-101 insulin like growth factor binding protein 5 Homo sapiens 37-44 12376561-8 2002 On plastic, neither IGFBP-3 nor -5 alone affected cell viability; although ceramide-induced apoptosis was enhanced by IGFBP-3 but reduced by IGFBP-5. Ceramides 75-83 insulin like growth factor binding protein 5 Homo sapiens 141-148 12074575-6 2002 In summary, all forms of IGFBP-5 modulated ceramide-induced apoptosis in Hs578T cells. Ceramides 43-51 insulin like growth factor binding protein 5 Homo sapiens 25-32 11835403-1 2002 We have demonstrated previously that IGFBP-5 can confer survival against apoptosis induced by ceramide, C2, or a small synthetic arginine-glycine-aspartic acid (RGD)-containing peptide in a direct manner. Ceramides 94-102 insulin like growth factor binding protein 5 Homo sapiens 37-44 11835403-12 2002 These data suggest that IGFBP-5 promotes the attachment and survival of Hs578T cells by modulating the balance between ceramide and opposing survival signals. Ceramides 119-127 insulin like growth factor binding protein 5 Homo sapiens 24-31