PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15474071-10 2004 CONCLUSION(S): The results suggest that IL-1alpha stimulates the production of IL-8 and M-CSF by a mechanism that involves the sphingomyelin-ceramide system. Ceramides 141-149 colony stimulating factor 1 Homo sapiens 88-93 15474071-0 2004 Synergistic effect of interleukin (IL)-1alpha and ceramide analogue on the production of IL-6, IL-8, and macrophage colony-stimulating factor by endometrial stromal cells. Ceramides 50-58 colony stimulating factor 1 Homo sapiens 105-141 19416641-1 2009 We previously reported that incubation of bone-marrow derived macrophages in the absence of macrophage-colony stimulating factor (M-CSF), a cytokine that is essential for their growth and survival, resulted in stimulation of acid sphingomyelinase, accumulation of ceramides, and induction of apoptosis [A. Gomez-Munoz et al. Ceramides 264-273 colony stimulating factor 1 Homo sapiens 130-135 15474071-11 2004 Ceramide may be important in increasing the production of IL-8 and M-CSF in the human endometrium. Ceramides 0-8 colony stimulating factor 1 Homo sapiens 67-72 12750385-11 2003 M-CSF deprivation resulted in activation of acid sphingomyelinase and an increase in ceramide levels. Ceramides 85-93 colony stimulating factor 1 Homo sapiens 0-5 14523050-13 2004 M-CSF deprivation resulted in activation of acid sphingomyelinase (A-SMase), increased ceramide levels, and a decrease in intracellular Cer-1-P. Exogenously added Cer-1-P inhibited A-SMase in intact BMDMs at concentrations that also prevented apoptosis. Ceramides 87-95 colony stimulating factor 1 Homo sapiens 0-5 12750385-13 2003 Ox-LDL completely blocked the increase in acid sphingomyelinase activity as well as the increase in ceramide after M-CSF deprivation. Ceramides 100-108 colony stimulating factor 1 Homo sapiens 115-120