PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21204761-3	2010	Inhibition of P-gp function by MDR1 shRNA and functional activity of hNIS gene was assessed using a 99(m)Tc sestamibi uptake and 125I uptake, respectively.	Technetium Tc 99m Sestamibi	108-117	phosphoglycolate phosphatase	Mus musculus	14-18	
19093112-8	2009	CONCLUSIONS: Quantified (99m)Tc-MIBI efflux has potential to: (1) noninvasively assign Mdr1 expression levels, (2) predict the therapeutic impact of a P-gp inhibitor, and (3) noninvasively assess the probability of drug resistance.	Technetium Tc 99m Sestamibi	29-36	phosphoglycolate phosphatase	Mus musculus	151-155	
19067785-4	2009	P-gp reduced (99m)Tc-MIBI transport across the BBB of P-gp-deficient mice 2.2-fold, as confirmed by PSC833 and GF120918 inhibition.	Technetium Tc 99m Sestamibi	18-25	phosphoglycolate phosphatase	Mus musculus	0-4	
19067785-4	2009	P-gp reduced (99m)Tc-MIBI transport across the BBB of P-gp-deficient mice 2.2-fold, as confirmed by PSC833 and GF120918 inhibition.	Technetium Tc 99m Sestamibi	18-25	phosphoglycolate phosphatase	Mus musculus	54-58	
19067785-8	2009	(99m)Tc-MIBI transport at the BBB is restricted by P-gp but not by Mrp1 or Bcrp.	Technetium Tc 99m Sestamibi	5-12	phosphoglycolate phosphatase	Mus musculus	51-55	
16955376-0	2006	99mTc-Sestamibi, a sensitive probe for in vivo imaging of P-glycoprotein inhibition by modulators and mdr1 antisense oligodeoxynucleotides.	Technetium Tc 99m Sestamibi	0-15	phosphoglycolate phosphatase	Mus musculus	58-72	
16955376-1	2006	PURPOSE: We tested the suitability of (99m)Tc-sestamibi to image the inhibition of P-glycoprotein (Pgp)-mediated multidrug resistance in tumor cells and xenografts after antisense treatment and/or inhibition with a novel Pgp modulator WK-X-34.	Technetium Tc 99m Sestamibi	43-55	phosphoglycolate phosphatase	Mus musculus	83-97	
16955376-1	2006	PURPOSE: We tested the suitability of (99m)Tc-sestamibi to image the inhibition of P-glycoprotein (Pgp)-mediated multidrug resistance in tumor cells and xenografts after antisense treatment and/or inhibition with a novel Pgp modulator WK-X-34.	Technetium Tc 99m Sestamibi	43-55	phosphoglycolate phosphatase	Mus musculus	99-102	
16955376-10	2006	CONCLUSIONS: (99m)Tc-sestamibi is a sensitive probe to monitor Pgp inhibition by different mechanisms in vivo in tumor xenografts.	Technetium Tc 99m Sestamibi	18-30	phosphoglycolate phosphatase	Mus musculus	63-66	
15967124-2	2005	The positron-emitting radiotracer hexakis(2-methoxyisobutylisonitrile)-(94m)Tc ((94m)Tc-MIBI) was synthesized and validated in cell transport studies as a substrate for MDR1 Pgp.	Technetium Tc 99m Sestamibi	85-92	phosphoglycolate phosphatase	Mus musculus	174-177	
15967124-3	2005	In vivo small-scale PET imaging and biodistribution studies of mdr1a/1b (-/-) gene deleted and wild-type mice demonstrated the use of (94m)Tc-MIBI to detect Pgp function.	Technetium Tc 99m Sestamibi	139-146	phosphoglycolate phosphatase	Mus musculus	157-160