PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35293347-11 2022 Finally, the expression and phosphorylation of STAT3 were down-regulated after a single or dual treatment with BEZ235 and R848. dactolisib 111-117 signal transducer and activator of transcription 3 Mus musculus 47-52 35293347-12 2022 CONCLUSION: Our results conclude that treatment with the combination of BEZ235 and R848 interferes with immune evasion mechanisms through STAT3-signaling pathway in WEHI-3 leukemia cells. dactolisib 72-78 signal transducer and activator of transcription 3 Mus musculus 138-143 33431808-10 2021 Both cancer cells and in vivo tumor xenografts showed that the combined inhibition of PI3K/AKT/mTOR and STAT3 activity enhanced the inhibitory effect of BEZ235 on the proliferation of PTEN-deficient cancer cells. dactolisib 153-159 signal transducer and activator of transcription 3 Mus musculus 104-109