PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26640144-6 2016 Knockdown of HMGA2, or suppressing HMGA2 expression with the histone deacetylase inhibitor LBH589, inhibits epithelial-mesenchymal plasticity and stemness activities in vitro and markedly reduces tumor growth and metastasis in vivo through successful targeting of EMT and mesenchymal-like tumor cells. Panobinostat 91-97 high mobility group AT-hook 2 Homo sapiens 35-40 25236537-5 2015 A histone deacetylase inhibitor, panobinostat, significantly increased MIRLET7 expression and reduced variant 1 of HMGA2 mRNA expression, but not variant 2, in both U937 cells and PMF-derived CD34(+) cells. Panobinostat 33-45 high mobility group AT-hook 2 Homo sapiens 115-120 22683924-3 2012 We here investigate whether HMGA2 (High Mobility Group AT-2 hook), a nuclear non-histone transcriptional co-factor with known oncogenic properties, can be influenced by the novel pan-deacetylase inhibitor panobinostat (LBH589) in human hepatocellular carcinoma models. Panobinostat 219-225 high mobility group AT-hook 2 Homo sapiens 28-33