PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23796028-0 2013 Inhibition of interleukin-13 gene expression by triptolide in activated T lymphocytes. triptolide 48-58 interleukin 13 Homo sapiens 14-28 23796028-2 2013 Our objective was to investigate the mechanism of the inhibitory effect of triptolide on interleukin-13 (IL-13) gene expression in activated T lymphocytes. triptolide 75-85 interleukin 13 Homo sapiens 89-103 23796028-2 2013 Our objective was to investigate the mechanism of the inhibitory effect of triptolide on interleukin-13 (IL-13) gene expression in activated T lymphocytes. triptolide 75-85 interleukin 13 Homo sapiens 105-110 23796028-10 2013 In Hut-78 cells, IL-13 mRNA and protein expression were increased with anti-CD3/CD28 stimulation and significantly inhibited by incubation with 28 nmol triptolide. triptolide 152-162 interleukin 13 Homo sapiens 17-22 23796028-11 2013 This concentration of triptolide also significantly inhibited the nuclear translocation of GATA3 and NFAT1 reducing the binding rate to the IL-13 gene promoter. triptolide 22-32 interleukin 13 Homo sapiens 140-145 23796028-12 2013 CONCLUSIONS: Triptolide inhibits IL-13 gene transcription and protein expression by inhibiting GATA3 and NFAT1 nuclear translocation and their binding rates to the IL-13 gene promoter region. triptolide 13-23 interleukin 13 Homo sapiens 33-38 23796028-12 2013 CONCLUSIONS: Triptolide inhibits IL-13 gene transcription and protein expression by inhibiting GATA3 and NFAT1 nuclear translocation and their binding rates to the IL-13 gene promoter region. triptolide 13-23 interleukin 13 Homo sapiens 164-169