PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15492464-3 2004 In the presence of forskolin or IBMX (3-isobutyl-1-methylxanthine), ET-1 produced a dual effect, that is, a positive inotropic effect (PIE) and/or a negative inotropic effect (NIE) depending on concentrations of forskolin or IBMX present simultaneously with ET-1. Colforsin 19-28 endothelin 1 Canis lupus familiaris 68-72 15492464-3 2004 In the presence of forskolin or IBMX (3-isobutyl-1-methylxanthine), ET-1 produced a dual effect, that is, a positive inotropic effect (PIE) and/or a negative inotropic effect (NIE) depending on concentrations of forskolin or IBMX present simultaneously with ET-1. Colforsin 19-28 endothelin 1 Canis lupus familiaris 258-262 15492464-3 2004 In the presence of forskolin or IBMX (3-isobutyl-1-methylxanthine), ET-1 produced a dual effect, that is, a positive inotropic effect (PIE) and/or a negative inotropic effect (NIE) depending on concentrations of forskolin or IBMX present simultaneously with ET-1. Colforsin 212-221 endothelin 1 Canis lupus familiaris 68-72 10874508-0 2000 Effects of NKH477 on endothelin-1-induced renal responses in anaesthetized dogs. Colforsin 11-17 endothelin 1 Canis lupus familiaris 21-33 10874508-4 2000 Intrarenal arterial infusion of endothelin (ET)-1 (2 ng/kg per min) reduced basal values of these parameters and glomerular filtration rate, which were recovered by the addition of NKH477 during ET-1 infusion. Colforsin 181-187 endothelin 1 Canis lupus familiaris 32-42 9788291-5 1998 While after treatment with forskolin for 24 h, the cells retained the ability to respond to ET-1-induced Ca2+ mobilization to the same extent as the control group. Colforsin 27-36 endothelin 1 Canis lupus familiaris 92-96 9788291-7 1998 Forskolin (1-100 microM) inhibited the ET-1-induced increase in [Ca2+]i, but the lower concentrations had little effect on this response. Colforsin 0-9 endothelin 1 Canis lupus familiaris 39-43 9788291-10 1998 The water-soluble forskolin analogue L-858051, 7-deacetyl-7beta-(gamma-N-methylpiperazino)-butyryl forskolin, significantly inhibited ET-1-stimulated IPs accumulation. Colforsin 18-27 endothelin 1 Canis lupus familiaris 134-138