PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33028758-2	2021	Fluctuations of Bmal1, Clock, Per2 and Cry1 mRNA levels were found in H295R cells treated with forskolin (FSK) in a serum-free condition.	Colforsin	95-104	clock circadian regulator	Homo sapiens	23-28	
30518737-2	2019	Similarities between changes in the mRNA and protein expression levels of Bmal1 and Clock and those of Per2 and Cry1 were found in KGN cells after treatment with forskolin.	Colforsin	162-171	clock circadian regulator	Homo sapiens	84-89	
30518737-4	2019	Knockdown of Clock gene by siRNA resulted in a significant reduction of estradiol production by inhibiting P450arom expression, while it induced a significant increase of progesterone production by upregulating 3betaHSD in KGN cells treated with forskolin.	Colforsin	246-255	clock circadian regulator	Homo sapiens	13-18	
33028758-2	2021	Fluctuations of Bmal1, Clock, Per2 and Cry1 mRNA levels were found in H295R cells treated with forskolin (FSK) in a serum-free condition.	Colforsin	106-109	clock circadian regulator	Homo sapiens	23-28	
33028758-3	2021	The changes of clock gene expression levels were diverged, with Clock mRNA level being significantly higher than Cry1 and Per2 mRNA levels after 12-h stimulation with FSK.	Colforsin	167-170	clock circadian regulator	Homo sapiens	15-20	
33028758-3	2021	The changes of clock gene expression levels were diverged, with Clock mRNA level being significantly higher than Cry1 and Per2 mRNA levels after 12-h stimulation with FSK.	Colforsin	167-170	clock circadian regulator	Homo sapiens	64-69	
33028758-6	2021	Knockdown of Clock gene by siRNA led to a significant reduction of FSK-induced expression of StAR and CYP17 after 12-h treatment with FSK.	Colforsin	67-70	clock circadian regulator	Homo sapiens	13-18	
33028758-6	2021	Knockdown of Clock gene by siRNA led to a significant reduction of FSK-induced expression of StAR and CYP17 after 12-h treatment with FSK.	Colforsin	134-137	clock circadian regulator	Homo sapiens	13-18	
33028758-8	2021	Collectively, the results indicated that changes of Clock mRNA expression, being upregulated by FSK and suppressed by BMP-6 and activin, were tightly linked to StAR expression by human adrenocortical cells.	Colforsin	96-99	clock circadian regulator	Homo sapiens	52-57	
30518737-6	2019	Thus, the expression levels of Clock, being upregulated by forskolin and BMP-7, were functionally linked to estradiol production and progesterone suppression by human granulosa cells.	Colforsin	59-68	clock circadian regulator	Homo sapiens	31-36