PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31801949-5	2019	Inhibition of PI3K and AKT using idelalisib and MK2206, respectively increased ibrutinib-induced apoptosis in IB-R cells by downregulation of pAKT473 and restoring FOXO3a levels, demonstrating the importance of these cell survival factors for ibrutinib-resistance.	idelalisib	33-43	forkhead box O3	Homo sapiens	164-170	
28125433-4	2017	CAL-101 also leads to induction of caspase-dependent apoptosis probably through reactive oxygen species-dependent upregulation of FOXO3a and subsequent induction of the proapoptotic target genes of p53.	idelalisib	0-7	forkhead box O3	Homo sapiens	130-136	
30224718-0	2018	Idelalisib promotes Bim-dependent apoptosis through AKT/FoxO3a in hepatocellular carcinoma.	idelalisib	0-10	forkhead box O3	Homo sapiens	56-62	
30224718-4	2018	Our results show that idelalisib treatment promotes Bim induction in HCC via the FoxO3a pathway following PI3K/AKT inactivation.	idelalisib	22-32	forkhead box O3	Homo sapiens	81-87