PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10748048-3	2000	Plasma and tissue levels of 25- and 27-hydroxycholesterol, two oxysterol substrates of this enzyme with potent regulatory actions in cultured cells, were markedly elevated in Cyp7b1(-/-) knockout animals.	Oxysterols	63-72	cytochrome P450, family 7, subfamily b, polypeptide 1	Mus musculus	175-181	
18055760-3	2008	In this study, we revealed a novel function of RORalpha (NR1F1) in regulating the oxysterol 7alpha-hydroxylase (Cyp7b1), an enzyme critical for the homeostasis of cholesterol, bile acids, and oxysterols.	Oxysterols	192-202	cytochrome P450, family 7, subfamily b, polypeptide 1	Mus musculus	82-110	
18055760-3	2008	In this study, we revealed a novel function of RORalpha (NR1F1) in regulating the oxysterol 7alpha-hydroxylase (Cyp7b1), an enzyme critical for the homeostasis of cholesterol, bile acids, and oxysterols.	Oxysterols	192-202	cytochrome P450, family 7, subfamily b, polypeptide 1	Mus musculus	112-118	
10748047-1	2000	The synthesis of 7alpha-hydroxylated bile acids from oxysterols requires an oxysterol 7alpha-hydroxylase encoded by the Cyp7b1 locus.	Oxysterols	53-63	cytochrome P450, family 7, subfamily b, polypeptide 1	Mus musculus	76-104	
10748047-1	2000	The synthesis of 7alpha-hydroxylated bile acids from oxysterols requires an oxysterol 7alpha-hydroxylase encoded by the Cyp7b1 locus.	Oxysterols	53-63	cytochrome P450, family 7, subfamily b, polypeptide 1	Mus musculus	120-126	
35303091-3	2022	We found upregulation of the oxysterol-producing enzymes CH25H and CYP7B1 and increased concentrations of 25-hydroxycholesterol upon Mtb infection in the lungs of mice.	Oxysterols	29-38	cytochrome P450, family 7, subfamily b, polypeptide 1	Mus musculus	67-73	
33008924-0	2020	Insulin resistance dysregulates CYP7B1 leading to oxysterol accumulation: a pathway for NAFL to NASH transition.	Oxysterols	50-59	cytochrome P450, family 7, subfamily b, polypeptide 1	Mus musculus	32-38	
24954418-2	2014	27-hydroxycholesterol (27HC) is an abundant oxysterol metabolized by CYP7B1.	Oxysterols	44-53	cytochrome P450, family 7, subfamily b, polypeptide 1	Mus musculus	69-75	
28928671-16	2017	In addition, the increase and reduction of Cyp27a1 and Cyp7b1 in trained mice may contribute to enhance levels of 27-OH C. Both oxysterols may act as an alternative pathway for the RCT contributing to the reduction of cholesterol in the aortic arch preventing atherogenesis.	Oxysterols	128-138	cytochrome P450, family 7, subfamily b, polypeptide 1	Mus musculus	55-61