PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24491562-0	2014	Oxysterols in the brain of the cholesterol 24-hydroxylase knockout mouse.	Oxysterols	0-10	cytochrome P450, family 46, subfamily a, polypeptide 1	Mus musculus	31-57	
24491562-3	2014	Despite a great reduction in the abundance of 24S-hydroxycholesterol, the dominant metabolite of cholesterol in wild type brain, no other cholesterol metabolite was found to quantitatively replace this oxysterol in the Cyp46a1-/- mouse.	Oxysterols	202-211	cytochrome P450, family 46, subfamily a, polypeptide 1	Mus musculus	219-226	
19654569-4	2010	The major exportable form of brain cholesterol is 24S-hydroxycholesterol, an oxysterol generated by the neuronal cholesterol 24-hydroxylase encoded by the CYP46A1 gene.	Oxysterols	77-86	cytochrome P450, family 46, subfamily a, polypeptide 1	Mus musculus	113-139	
19654569-4	2010	The major exportable form of brain cholesterol is 24S-hydroxycholesterol, an oxysterol generated by the neuronal cholesterol 24-hydroxylase encoded by the CYP46A1 gene.	Oxysterols	77-86	cytochrome P450, family 46, subfamily a, polypeptide 1	Mus musculus	155-162	
18068744-9	2008	Perhaps surprisingly, the retina expresses CYP 27A1 and CYP 46A1, enzymes with broad substrate specificity for ring-modified sterols, implying that, in addition to a rich blood supply for disposing of potentially toxic oxysterols, they can be detoxified locally.	Oxysterols	219-229	cytochrome P450, family 46, subfamily a, polypeptide 1	Mus musculus	56-64	
32698250-3	2021	CYP27A1 and CYP46A1 are the major oxysterol-producing enzymes in the retina that convert cholesterol to 27- and 24-hydroxycholesterol, respectively.	Oxysterols	34-43	cytochrome P450, family 46, subfamily a, polypeptide 1	Mus musculus	12-19	
31541728-0	2019	Formation and metabolism of oxysterols and cholestenoic acids found in the mouse circulation: Lessons learnt from deuterium-enrichment experiments and the CYP46A1 transgenic mouse.	Oxysterols	28-38	cytochrome P450, family 46, subfamily a, polypeptide 1	Mus musculus	155-162