PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20664003-4 2010 To test this hypothesis we have begun to obtain structural information about family B GPCRs, using as a prototype the CRF(1), by determining the ability of sulfhydryl-specific methanethiosulfonate derivatives, such as the methanethiosulfonate-ethylammonium (MTSEA), to react with CRF(1) and thus irreversibly inhibit (125)I-Tyr(0)-sauvagine binding. methanethiosulfonate 176-196 corticotropin releasing hormone receptor 1 Homo sapiens 118-124 20664003-4 2010 To test this hypothesis we have begun to obtain structural information about family B GPCRs, using as a prototype the CRF(1), by determining the ability of sulfhydryl-specific methanethiosulfonate derivatives, such as the methanethiosulfonate-ethylammonium (MTSEA), to react with CRF(1) and thus irreversibly inhibit (125)I-Tyr(0)-sauvagine binding. methanethiosulfonate 176-196 corticotropin releasing hormone receptor 1 Homo sapiens 280-286