PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21294903-3 2011 The current study examined breast cancer as a metabolic disease in the context of altered fatty acid catabolism by examining the effect of PRL on carnitine palmitoyl transferase 1 (CPT1), an enzyme that shuttles long-chain fatty acids into the mitochondrial matrix for beta-oxidation. long-chain fatty acids 212-234 carnitine palmitoyltransferase 1A Homo sapiens 181-185 12464674-3 2002 We hypothesized that the transfer of long-chain fatty acids (LCFAs) into the mitochondria via carnitine palmitoyltransferase-1 (CPT-1) is inhibited by increased malonyl coenzyme A (malonyl-CoA) (a known potent inhibitor of CPT-1) in human muscle during hyperglycemia with hyperinsulinemia. long-chain fatty acids 37-59 carnitine palmitoyltransferase 1A Homo sapiens 94-126 17445541-2 2007 The carnitine palmitoyltransferase (CPT) enzyme system facilitates the transport of long-chain fatty acids into mitochondria, and the gene for the hepatic isoform of CPT1 (CPT1A) is a candidate gene for metabolic disorders such as insulin resistance associated with fatty liver. long-chain fatty acids 84-106 carnitine palmitoyltransferase 1A Homo sapiens 166-170 17445541-2 2007 The carnitine palmitoyltransferase (CPT) enzyme system facilitates the transport of long-chain fatty acids into mitochondria, and the gene for the hepatic isoform of CPT1 (CPT1A) is a candidate gene for metabolic disorders such as insulin resistance associated with fatty liver. long-chain fatty acids 84-106 carnitine palmitoyltransferase 1A Homo sapiens 172-177 20357432-2 2010 Increased malonyl coenzyme A production which compromises oxidation of long-chain fatty acids via carnitine palmitoyltransferase (CPT) 1 inhibition plays a crucial role in the pathogenesis of these complications. long-chain fatty acids 71-93 carnitine palmitoyltransferase 1A Homo sapiens 98-136 18253084-1 2007 Carnitine palmitoyl transferase I (CPT1) catalyzes the transport of long-chain fatty acids into mitochondria for beta-oxidation. long-chain fatty acids 68-90 carnitine palmitoyltransferase 1A Homo sapiens 35-39 12464674-3 2002 We hypothesized that the transfer of long-chain fatty acids (LCFAs) into the mitochondria via carnitine palmitoyltransferase-1 (CPT-1) is inhibited by increased malonyl coenzyme A (malonyl-CoA) (a known potent inhibitor of CPT-1) in human muscle during hyperglycemia with hyperinsulinemia. long-chain fatty acids 37-59 carnitine palmitoyltransferase 1A Homo sapiens 128-133 12464674-3 2002 We hypothesized that the transfer of long-chain fatty acids (LCFAs) into the mitochondria via carnitine palmitoyltransferase-1 (CPT-1) is inhibited by increased malonyl coenzyme A (malonyl-CoA) (a known potent inhibitor of CPT-1) in human muscle during hyperglycemia with hyperinsulinemia. long-chain fatty acids 37-59 carnitine palmitoyltransferase 1A Homo sapiens 223-228 30016793-1 2018 BACKGROUND/AIMS: Carnitine palmitoyltransferase 1A (CPT1A) is a rate-limiting enzyme in the transport of long-chain fatty acids for beta-oxidation. long-chain fatty acids 105-127 carnitine palmitoyltransferase 1A Homo sapiens 17-50 12189492-2 2002 CPT1 controls the import of long-chain fatty acids into the mitochondria, where they are oxidized. long-chain fatty acids 28-50 carnitine palmitoyltransferase 1A Homo sapiens 0-4 29664569-4 2018 Moreover, it has been proposed that CD8+ Tmem cells have a specific requirement for the oxidation of long-chain fatty acids (LC-FAO), a process modulated in lymphocytes by the enzyme CPT1A. long-chain fatty acids 101-123 carnitine palmitoyltransferase 1A Homo sapiens 183-188 29433421-3 2018 CPT1A encodes a protein that imports long-chain fatty acids into the mitochondria for fatty-acid oxidation. long-chain fatty acids 37-59 carnitine palmitoyltransferase 1A Homo sapiens 0-5 29596410-8 2018 Taken together, these results suggest that transport of at least some long-chain fatty acids into the mitochondria by CPT1 may be required for anabolic processes that support healthy mitochondrial function and cancer cell proliferation independent of FAO. long-chain fatty acids 70-92 carnitine palmitoyltransferase 1A Homo sapiens 118-122 30016793-1 2018 BACKGROUND/AIMS: Carnitine palmitoyltransferase 1A (CPT1A) is a rate-limiting enzyme in the transport of long-chain fatty acids for beta-oxidation. long-chain fatty acids 105-127 carnitine palmitoyltransferase 1A Homo sapiens 52-57 26799588-2 2016 Carnitine palmitoyl transferase I (CPT1) is the rate-limiting enzyme in the transport of long-chain fatty acids for beta-oxidation. long-chain fatty acids 89-111 carnitine palmitoyltransferase 1A Homo sapiens 35-39 28125087-1 2017 Carnitine palmitoyltransferase 1 isoform A (CPT1A) is a crucial enzyme for the transport of long-chain fatty acids into the mitochondria. long-chain fatty acids 92-114 carnitine palmitoyltransferase 1A Homo sapiens 0-42 28125087-1 2017 Carnitine palmitoyltransferase 1 isoform A (CPT1A) is a crucial enzyme for the transport of long-chain fatty acids into the mitochondria. long-chain fatty acids 92-114 carnitine palmitoyltransferase 1A Homo sapiens 44-49 24118240-4 2013 Among the many metabolite changes detected, the most characteristic metabolites uniquely indicated carnitine palmitoyltransferase-1 (CPT1), the critical enzyme for mitochondrial beta-oxidation of long-chain fatty acids, to be a target for oxidative inactivation. long-chain fatty acids 196-218 carnitine palmitoyltransferase 1A Homo sapiens 99-131 26798409-8 2016 CPT1A holds a cardinal position in the metabolism of long-chain fatty acids while ABCG1 plays a role in triglyceride metabolism. long-chain fatty acids 53-75 carnitine palmitoyltransferase 1A Homo sapiens 0-5 26708865-2 2016 CPT1A and CPT1B were identified as the gate-keeper enzymes for the entry of long-chain fatty acids (as carnitine esters) into mitochondria and their further oxidation, and they show differences in their kinetics and tissue expression. long-chain fatty acids 76-98 carnitine palmitoyltransferase 1A Homo sapiens 0-5 24118240-4 2013 Among the many metabolite changes detected, the most characteristic metabolites uniquely indicated carnitine palmitoyltransferase-1 (CPT1), the critical enzyme for mitochondrial beta-oxidation of long-chain fatty acids, to be a target for oxidative inactivation. long-chain fatty acids 196-218 carnitine palmitoyltransferase 1A Homo sapiens 133-137