PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12705905-0	2003	Guggulsterone antagonizes farnesoid X receptor induction of bile salt export pump but activates pregnane X receptor to inhibit cholesterol 7alpha-hydroxylase gene.	pregna-4,17-diene-3,16-dione	0-13	cytochrome P450 family 7 subfamily A member 1	Homo sapiens	127-157	
22246918-4	2012	In this study, we tested whether Z-guggulsterone indeed induces human CYP7A1.	pregna-4,17-diene-3,16-dione	33-48	cytochrome P450 family 7 subfamily A member 1	Homo sapiens	70-76	
12705905-4	2003	On the other hand, guggulsterone has no effect on FXR inhibition of the CYP7A1 gene, but strongly inhibits the human CYP7A1 gene by activation of pregnane X receptor (PXR).	pregna-4,17-diene-3,16-dione	19-32	cytochrome P450 family 7 subfamily A member 1	Homo sapiens	117-123