PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22649756-8	2011	ERalpha down-regulation in response to GS suggests that it can be of potential use in the treatment of estrogen positive tumors that are resistant to tamoxifen.	pregna-4,17-diene-3,16-dione	39-41	estrogen receptor 1	Homo sapiens	0-7	
15075359-5	2004	Here, we show that guggulsterones activate the estrogen receptor alpha isoform, progesterone receptor, and pregnane X receptor.	pregna-4,17-diene-3,16-dione	19-33	estrogen receptor 1	Homo sapiens	47-70	
15075359-11	2004	Moreover, our data suggest the need for additional studies of guggulsterones agonist activity against estrogen receptor alpha isoform and the progesterone receptor.	pregna-4,17-diene-3,16-dione	62-76	estrogen receptor 1	Homo sapiens	102-125