PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30652318-5	2019	In contrast, atorvastatin, bosentan, etoposide, fexofenadine, fluvastatin, glibenclamide and simeprevir were broadly transported by recombinant monkey OATP1B1, OATP1B3 and OATP2B1.	Simeprevir	93-103	solute carrier organic anion transporter family member 1B1	Homo sapiens	151-158	
27896690-1	2017	The disposition of simeprevir (SMV) in humans is characterised by cytochrome P450 3A4 metabolism and hepatic uptake by organic anion transporting polypeptide 1B1/3 (OATP1B1/3).	Simeprevir	19-29	solute carrier organic anion transporter family member 1B1	Homo sapiens	165-172	
27896690-1	2017	The disposition of simeprevir (SMV) in humans is characterised by cytochrome P450 3A4 metabolism and hepatic uptake by organic anion transporting polypeptide 1B1/3 (OATP1B1/3).	Simeprevir	31-34	solute carrier organic anion transporter family member 1B1	Homo sapiens	165-172	
26259716-6	2016	Saturation of gut and liver metabolism by CYP3A4, and saturation of hepatic uptake by OATP1B1/3, seem to account for the observed nonlinear PK of simeprevir.	Simeprevir	146-156	solute carrier organic anion transporter family member 1B1	Homo sapiens	86-93	
26353895-7	2016	Simeprevir is a substrate and inhibitor of the transporters P-glycoprotein (P-gp), breast cancer resistance protein (BCRP) and OATP1B1/3.	Simeprevir	0-10	solute carrier organic anion transporter family member 1B1	Homo sapiens	127-134	
24867984-6	2014	The results of our coincubation inhibition assays have shown that all tested DAAs could inhibit OATP1B1 functions and that SMV, ASV, and DCV (to a lesser extent), but not SFV, exhibited long-lasting preincubation inhibitory effects on OATP1B1 functions.	Simeprevir	123-126	solute carrier organic anion transporter family member 1B1	Homo sapiens	235-242