PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31964792-0	2020	Ceftazidime-avibactam resistance associated with increased bla KPC-3 gene copy number mediated by pKpQIL plasmid derivatives in ST258 Klebsiella pneumoniae.	avibactam, ceftazidime drug combination	0-21	KPC-3	Klebsiella pneumoniae	63-68	
33558042-6	2021	Two KPC-3 variants showed CZA resistance with sustained carbapenemase activity without genomic adaptations in the KPC gene.	avibactam, ceftazidime drug combination	26-29	KPC-3	Klebsiella pneumoniae	4-9	
34228551-5	2021	In this study, we evaluated in vitro the nature of the mutations in the KPC-2 and KPC-3 ss-lactamase sequences (the most frequent KPC-type enzymes) that lead to CZA resistance, and the subsequent effects of these mutations on susceptibility to other ss-lactam antibiotics.	avibactam, ceftazidime drug combination	161-164	KPC-3	Klebsiella pneumoniae	82-87	
34988712-8	2022	An interplay between highly conserved KPC-31- and KPC-3-producing ST2502 strains occurred in the SARS-CoV2 patient during the hospitalization, selected by CZA and carbapenem treatments, respectively.	avibactam, ceftazidime drug combination	155-158	KPC-3	Klebsiella pneumoniae	50-55