PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34592904-2 2021 To start with, the network pharmacology approach and molecular docking technology were used to uncover all candidate targets of oxyresveratrol to treat liver cancer, accompanied with identified anti-liver cancer targets including estrogen receptor 1 (ESR1), epidermal growth factor receptor (EGFR). puag-haad 128-142 estrogen receptor 1 Homo sapiens 230-249 34592904-2 2021 To start with, the network pharmacology approach and molecular docking technology were used to uncover all candidate targets of oxyresveratrol to treat liver cancer, accompanied with identified anti-liver cancer targets including estrogen receptor 1 (ESR1), epidermal growth factor receptor (EGFR). puag-haad 128-142 estrogen receptor 1 Homo sapiens 251-255 34592904-5 2021 The in-vitro data indicated that intracellular contents of ESR1, EGFR mRNAs in oxyresveratrol-treated liver cancer cells were reduced. puag-haad 79-93 estrogen receptor 1 Homo sapiens 59-63 28484893-0 2017 Oxyresveratrol Is a Phytoestrogen Exerting Anti-inflammatory Effects Through NF-kappaB and Estrogen Receptor Signaling. puag-haad 0-14 estrogen receptor 1 Homo sapiens 91-108 28484893-3 2017 In MCF-7 cells, oxyresveratrol significantly induced proliferation, which was accompanied with estrogen receptor (ER)-mediated transcriptional activation, increased estrogen-targeted gene expression (e.g., pS2, PGR, and CTSD), and increased ERalpha/beta proteins. puag-haad 16-30 estrogen receptor 1 Homo sapiens 95-112 28484893-3 2017 In MCF-7 cells, oxyresveratrol significantly induced proliferation, which was accompanied with estrogen receptor (ER)-mediated transcriptional activation, increased estrogen-targeted gene expression (e.g., pS2, PGR, and CTSD), and increased ERalpha/beta proteins. puag-haad 16-30 estrogen receptor 1 Homo sapiens 114-116 28484893-4 2017 The estrogen-like effect of oxyresveratrol was reversed by the ER inhibitor ICI 182780. puag-haad 28-42 estrogen receptor 1 Homo sapiens 63-65 28484893-5 2017 Strong ER-binding activities of oxyresveratrol were revealed by negative docking scores. puag-haad 32-46 estrogen receptor 1 Homo sapiens 7-9