PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25982816-2 2015 Our study reveals that the TGFBR1 inhibitor SD208 effectively reduces prostate cancer bone metastases. SD-208 44-49 transforming growth factor beta receptor 1 Homo sapiens 27-33 16575856-1 2006 OBJECTIVE: To use a specific transforming growth factor beta receptor type I (TGFbetaRI; activin receptor-like kinase 5 [ALK-5]) kinase inhibitor (SD208) to determine the role of activation of the TGFbetaRI kinase (ALK-5) in maintaining the profibrotic phenotype of dermal fibroblasts in systemic sclerosis (SSc). SD-208 147-152 transforming growth factor beta receptor 1 Homo sapiens 29-119 21465486-4 2011 Therefore, we assessed the effect of the disruption of TGF-beta/ALK5/Smad signalling by an ALK5 inhibitor (SD-208) in two experimental animal models of intestinal fibrosis: anaerobic bacteria- and trinitrobenzensulphonic acid-induced colitis. SD-208 107-113 transforming growth factor beta receptor 1 Homo sapiens 64-68 21465486-4 2011 Therefore, we assessed the effect of the disruption of TGF-beta/ALK5/Smad signalling by an ALK5 inhibitor (SD-208) in two experimental animal models of intestinal fibrosis: anaerobic bacteria- and trinitrobenzensulphonic acid-induced colitis. SD-208 107-113 transforming growth factor beta receptor 1 Homo sapiens 91-95 18229422-3 2007 Previously, we reported that treatment of pancreatic cancer cells in vitro with SD-208, a small molecule inhibitor of the TGF-beta receptor I kinase (TGF-betaRI), inhibited expression of genes associated with tumor progression and inhibited invasiveness in a cell-based assay. SD-208 80-86 transforming growth factor beta receptor 1 Homo sapiens 122-148 18229422-3 2007 Previously, we reported that treatment of pancreatic cancer cells in vitro with SD-208, a small molecule inhibitor of the TGF-beta receptor I kinase (TGF-betaRI), inhibited expression of genes associated with tumor progression and inhibited invasiveness in a cell-based assay. SD-208 80-86 transforming growth factor beta receptor 1 Homo sapiens 150-160 16575856-1 2006 OBJECTIVE: To use a specific transforming growth factor beta receptor type I (TGFbetaRI; activin receptor-like kinase 5 [ALK-5]) kinase inhibitor (SD208) to determine the role of activation of the TGFbetaRI kinase (ALK-5) in maintaining the profibrotic phenotype of dermal fibroblasts in systemic sclerosis (SSc). SD-208 147-152 transforming growth factor beta receptor 1 Homo sapiens 78-87 32443848-6 2020 Fibrotic phenotype of cardiac microtissues was inhibited by treatment with TGF-beta-receptor type 1 inhibitor SD208 in a dose-dependent manner. SD-208 110-115 transforming growth factor beta receptor 1 Homo sapiens 75-99