PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19200051-2 2009 In the present investigation, we analyzed the role of EGFR signaling pathways for the activity of artesunate towards cancer cells. Artesunate 98-108 epidermal growth factor receptor Homo sapiens 54-58 19200051-3 2009 The microarray-based mRNA expression of genes involved in EGFR signaling pathway was correlated with the 50% inhibition concentrations (IC<inf>50</<inf>) of 55 tumor cell lines for artesunate. Artesunate 196-206 epidermal growth factor receptor Homo sapiens 58-62 29174651-7 2017 CONCLUSION: The combination of natural products (e.g. the sesquiterpenoid artesunate) and synthetic compounds (e.g. the small molecule EGFR tyrosine kinase inhibitor erlotinib) may lead to improved clinical success rates in oncology. Artesunate 74-84 epidermal growth factor receptor Homo sapiens 135-139 22183882-0 2011 The effects of artesunate on the expression of EGFR and ABCG2 in A549 human lung cancer cells and a xenograft model. Artesunate 15-25 epidermal growth factor receptor Homo sapiens 47-51 22183882-5 2011 Furthermore, artesunate down-regulated the expression of epidermal growth factor receptor (EGFR), Akt and ATP-binding cassette subfamily G member 2 (ABCG2) at the mRNA and protein levels in vitro and in vivo. Artesunate 13-23 epidermal growth factor receptor Homo sapiens 57-89 22183882-5 2011 Furthermore, artesunate down-regulated the expression of epidermal growth factor receptor (EGFR), Akt and ATP-binding cassette subfamily G member 2 (ABCG2) at the mRNA and protein levels in vitro and in vivo. Artesunate 13-23 epidermal growth factor receptor Homo sapiens 91-95 15878303-6 2005 Anti-oxidant stress genes (thioredoxin, catalase, gamma-glutamyl-cysteine synthetase, glutathione S-transferases) as well as the epidermal growth factor receptor confer resistance to artesunate. Artesunate 183-193 epidermal growth factor receptor Homo sapiens 129-161