PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32504784-0 2020 Ginsenoside Rg1 prevents vascular intimal hyperplasia involved by SDF-1alpha/CXCR4, SCF/c-kit and FKN/CX3CR1 axes in a rat balloon injury. ginsenoside Rg1 0-15 C-X3-C motif chemokine ligand 1 Rattus norvegicus 98-101 32504784-7 2020 AIM OF THE STUDY: This study was aimed to investigate whether GS-Rg1 prevented vascular intimal hyperplasia, and the involvement of stromal cell-derived factor-1alpha (SDF-1alpha)/CXCR4, stem cell factor (SCF)/c-kit and fractalkine (FKN)/CX3CR1 axes. ginsenoside Rg1 62-68 C-X3-C motif chemokine ligand 1 Rattus norvegicus 220-231 32504784-7 2020 AIM OF THE STUDY: This study was aimed to investigate whether GS-Rg1 prevented vascular intimal hyperplasia, and the involvement of stromal cell-derived factor-1alpha (SDF-1alpha)/CXCR4, stem cell factor (SCF)/c-kit and fractalkine (FKN)/CX3CR1 axes. ginsenoside Rg1 62-68 C-X3-C motif chemokine ligand 1 Rattus norvegicus 233-236 32504784-15 2020 Furthermore, GS-Rg1 8 mg/kg group and 16 mg/kg group decreased the protein expressions of the SDF-1alpha/CXCR4, SCF/c-kit and FKN/CX3CR1 axes in neointima, meanwhile GS-Rg1 8 mg/kg group and 16 mg/kg group also attenuated the expressions of SDF-1alpha, SCF and sFKN in serum. ginsenoside Rg1 13-19 C-X3-C motif chemokine ligand 1 Rattus norvegicus 126-129 32504784-17 2020 CONCLUSIONS: GS-Rg1 has a positive effect on inhibiting vascular intimal hyperplasia, and the underlying mechanism is related to inhibitory expression of SDF-1alpha/CXCR4, SCF/c-kit and FKN/CX3CR1 axes. ginsenoside Rg1 13-19 C-X3-C motif chemokine ligand 1 Rattus norvegicus 186-189