PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22728092-8 2012 Ginsenoside Rg1 and E2-treatment increased ADAM 10 level while reduced BACE 1 level and apoptosis. ginsenoside Rg1 0-15 ADAM metallopeptidase domain 10 Rattus norvegicus 43-50 31016510-11 2019 Administration of Rg1 effectively rescued the cognitive impairment and neuronal loss, and inhibited the beta-secretase processing of APP through reducing APP-Thr668 phosphorylation and BACE1/PS1 expression, and increasing the expression of ADAM10 and IDE. ginsenoside Rg1 18-21 ADAM metallopeptidase domain 10 Rattus norvegicus 240-246