PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26517938-1 2016 Brassinosteroid (BR) binding activates the receptor kinase BRI1 by inducing heterodimerization with its co-receptor kinase BAK1; however, the mechanisms that reversibly inactivate BRI1 remain unclear. Brassinosteroids 0-15 BCL2 antagonist/killer 1 Homo sapiens 123-127 26802250-5 2016 Further analyses indicated that TWD1 modulates the BR signal transduction not by altering ER quality control or protein abundance of BRI1; instead, TWD1 appears to be critical in BR-induced interaction of BRI1 and its co-receptor BAK1, as well as BR-induced phosphorylation of these two proteins. Brassinosteroids 51-53 BCL2 antagonist/killer 1 Homo sapiens 230-234 26517938-1 2016 Brassinosteroid (BR) binding activates the receptor kinase BRI1 by inducing heterodimerization with its co-receptor kinase BAK1; however, the mechanisms that reversibly inactivate BRI1 remain unclear. Brassinosteroids 17-19 BCL2 antagonist/killer 1 Homo sapiens 123-127 24308570-5 2013 Genetic and structural analyses indicated that BAK1 and its homologs play indispensible roles in mediating brassinosteroid (BR) signaling pathway by directly perceiving the ligand BR and activating the receptor of BR, BRI1. Brassinosteroids 107-122 BCL2 antagonist/killer 1 Homo sapiens 47-51 19704566-1 2008 BAK1 and BKK1 are two functionally redundant leucine-rich repeat receptor-like protein kinases (LRR-RLKs) involved in brassinosteroid signal transduction by their direct interactions with the BR receptor, BRI1. Brassinosteroids 118-133 BCL2 antagonist/killer 1 Homo sapiens 0-4 19748302-3 2009 Since its first description in 2001, several independent groups have discovered BAK1/SERK3 as a component of diverse processes, including brassinosteroid signaling, light responses, cell death, and plant innate immunity. Brassinosteroids 138-153 BCL2 antagonist/killer 1 Homo sapiens 80-84 19532123-0 2009 Membrane steroid-binding protein 1 (MSBP1) negatively regulates brassinosteroid signaling by enhancing the endocytosis of BAK1. Brassinosteroids 64-79 BCL2 antagonist/killer 1 Homo sapiens 122-126 18694562-0 2008 Sequential transphosphorylation of the BRI1/BAK1 receptor kinase complex impacts early events in brassinosteroid signaling. Brassinosteroids 97-112 BCL2 antagonist/killer 1 Homo sapiens 44-48 18694562-1 2008 Brassinosteroids (BRs) regulate plant development through a signal transduction pathway involving the BRI1 and BAK1 transmembrane receptor kinases. Brassinosteroids 0-16 BCL2 antagonist/killer 1 Homo sapiens 111-115 18694562-1 2008 Brassinosteroids (BRs) regulate plant development through a signal transduction pathway involving the BRI1 and BAK1 transmembrane receptor kinases. Brassinosteroids 18-21 BCL2 antagonist/killer 1 Homo sapiens 111-115 18694562-3 2008 We demonstrate that BR-dependent activation of BRI1 precedes association with BAK1 in planta, and that BRI1 positively regulates BAK1 phosphorylation levels in vivo. Brassinosteroids 20-22 BCL2 antagonist/killer 1 Homo sapiens 78-82 16699538-3 2006 Recent studies have demonstrated that BR binding to the extracellular domain of BRI1 induces kinase activation and dimerization with another receptor kinase, BAK1. Brassinosteroids 38-40 BCL2 antagonist/killer 1 Homo sapiens 158-162 33964457-4 2021 Using the RiD-receptors, we demonstrated that the rapamycin-mediated association of chimeric cytosolic kinase domains from the BRI1/BAK1 receptor/co-receptor, but not the BRI1/BRI1 or BAK1/BAK1 homodimer, is sufficient to activate downstream brassinosteroid signaling and physiological responses and that the engineered RiD-FLS2/BAK1 activates flagellin-22-mediated immune signaling and responses. Brassinosteroids 242-257 BCL2 antagonist/killer 1 Homo sapiens 132-136