PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23912246-11 2013 CONCLUSIONS: Perifosine inhibits the growth of gastric cancer cells possibly through inhibition of the Akt/GSK3beta/C-MYC signaling pathway-mediated down-regulation of AEG-1 that subsequently down-regulated cyclin D1. perifosine 13-23 cyclin D1 Homo sapiens 207-216 22438101-3 2012 Further, perifosine and curcumin synergistically increase intracellular level of reactive oxygen species and ceramide, and downregulate the expression of cyclin D1 and Bcl-2 in colorectal cancer cells. perifosine 9-19 cyclin D1 Homo sapiens 154-163