PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24059944-8 2013 After adjusting for baseline differences, fingolimod was associated with a 52% reduction in the probability of having a relapse (odds ratio, 0.48; 95% confidence interval [CI], 0.28-0.84; p = 0.0097) and a 50% reduction in ARR (rate ratio, 0.50; 95% CI, 0.34-0.75; p = 0.0006) compared with IFN/GA. Fingolimod Hydrochloride 42-52 interferon alpha 1 Homo sapiens 291-297 26111826-8 2016 After switching to fingolimod (M0-12 vs M13-EOS), patients initially treated with IFN had a 50% reduction in ARR (0.40 vs 0.20), reduced MRI activity and a lower rate of brain volume loss. Fingolimod Hydrochloride 19-29 interferon alpha 1 Homo sapiens 82-85 26111826-9 2016 In a post hoc analysis, the proportion of IFN-switch patients with no evidence of disease activity increased by approximately 50% in the first year after switching to fingolimod treatment (44.3% to 66.0%). Fingolimod Hydrochloride 167-177 interferon alpha 1 Homo sapiens 42-45 29854416-7 2018 Regardless of age, fingolimod-treated patients were more likely to achieve NEDA-3 versus placebo/IFN beta-1a, with strongest benefits in the youngest patients (all p < 0.05). Fingolimod Hydrochloride 19-29 interferon alpha 1 Homo sapiens 97-100