PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21687504-7 2011 Another putative S1P(1/3) receptor antagonist, VPC23019, does not inhibit S1P(3)-mediated vasoconstriction. VPC23019 47-55 sphingosine-1-phosphate receptor 1 Mus musculus 17-20 25930666-6 2015 hmSMC migration and DNA synthesis elicited by W6/32 were inhibited by the sphingosine kinase-1 (SK1) inhibitor dimethylsphingosine, the anti-S1P antibody Sphingomab and the S1PR1/R3 inhibitor VPC23019. VPC23019 192-200 sphingosine-1-phosphate receptor 1 Mus musculus 173-178 22913344-9 2013 All of these inhibitors except VPC23019 and nifedipine significantly reduced the S1P-induced tonic contractions. VPC23019 31-39 sphingosine-1-phosphate receptor 1 Mus musculus 81-84 19433984-3 2009 S1P stimulation of ERK was completely inhibited by an S1P1/3 subtype receptor antagonist (VPC23019), by a Gi protein inhibitor (pertussis toxin) and by a mitogen-activated protein kinase/ERK kinase inhibitor (PD98059). VPC23019 90-98 sphingosine-1-phosphate receptor 1 Mus musculus 0-3 30629456-3 2019 When ApoM-overexpressing HIGA mice were treated with VPC23019, an antagonist against S1P receptor 1 (S1P1) and 3 (S1P3), we observed that the protective effects of ApoM were reversed, whereas JTE013, an antagonist against S1P2, did not inhibit the effects. VPC23019 53-61 sphingosine-1-phosphate receptor 1 Mus musculus 85-99 17898040-5 2007 This protection with isoflurane was reversed by SK inhibitors (DMS and SKI-II) as well as an S1P(1) receptor antagonist (VPC23019). VPC23019 121-129 sphingosine-1-phosphate receptor 1 Mus musculus 93-96 32194396-11 2020 The S1P1 antagonist VPC23019 blocked the stimulatory effects of nmFGF1, whereas the S1P1 agonist FTY720 exerted effects comparable with those of nmFGF1. VPC23019 20-28 sphingosine-1-phosphate receptor 1 Mus musculus 4-8 30629456-3 2019 When ApoM-overexpressing HIGA mice were treated with VPC23019, an antagonist against S1P receptor 1 (S1P1) and 3 (S1P3), we observed that the protective effects of ApoM were reversed, whereas JTE013, an antagonist against S1P2, did not inhibit the effects. VPC23019 53-61 sphingosine-1-phosphate receptor 1 Mus musculus 101-105 29669385-6 2018 Treatment with VPC23019, an antagonist against S1P receptor 1 and 3, or LY294002, a PI3K inhibitor, partially reversed these protective properties arising from the overexpression of apoM. VPC23019 15-23 sphingosine-1-phosphate receptor 1 Mus musculus 47-67