PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9122357-7 1997 Recent research in nonhuman primates has characterized the behavioral, respiratory and cardiovascular effects of a number of xanthines and related drugs differing in affinity at different subtypes of adenosine receptors and in capacity to inhibit different molecular forms of PDE. Xanthines 125-134 aldehyde dehydrogenase 7 family member A1 Homo sapiens 276-279 9122357-8 1997 The behavioral-stimulant effects of xanthines appear to be mediated principally by their adenosine-antagonist actions and may be limited by PDE inhibition. Xanthines 36-45 aldehyde dehydrogenase 7 family member A1 Homo sapiens 140-143 9122357-9 1997 The respiratory-stimulant and cardiac effects of xanthines, on the other hand, appear to be linked more closely to their PDE-inhibiting actions than to adenosine antagonism. Xanthines 49-58 aldehyde dehydrogenase 7 family member A1 Homo sapiens 121-124 9122357-10 1997 Converging lines of evidence suggest that adenosine A2 and cAMP-specific (possibly type IV) PDE mechanisms play especially prominent roles in mediating the behavioral and physiological effects of xanthines in nonhuman primates. Xanthines 196-205 aldehyde dehydrogenase 7 family member A1 Homo sapiens 92-95