PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27292614-9	2016	In DU145 cells, TBMS1 induced mitochondrial apoptosis, evidenced by ROS generation, mitochondrial dysfunction, endoplasmic reticulum stress, modulated Bcl-2 family protein and cleaved caspase-3, and activated ASK-1 and its downstream targets p38 and JNK.	tubeimoside I	16-21	mitogen-activated protein kinase 14	Homo sapiens	242-245	
27292614-12	2016	Moreover, co-treatment with NAC (ROS scavenger), SB203580 (p38 inhibitor), SP600125 (JNK inhibitor) or salubrinal (ER stress inhibitor) significantly attenuated TBMS1-induced apoptosis.	tubeimoside I	161-166	mitogen-activated protein kinase 14	Homo sapiens	59-62	
26722392-6	2015	And TBMS1 also found to increase the phosphorylation, of JNK and p38, suggesting TBMS1 could activate the MAPK-JNK signaling pathway.	tubeimoside I	4-9	mitogen-activated protein kinase 14	Homo sapiens	65-68