PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34477530-3 2022 METHODS: The dose-effect of maslinic acid on HeLa cells, a human cervical cancer cell line, was first evaluated, including cytotoxicity, IL-6 secretion, IL-6 receptor (IL-6R) expression, proliferation potential and apoptosis status. maslinic acid 28-41 interleukin 6 Homo sapiens 137-141 34477530-5 2022 RESULTS: Maslinic acid dose-dependently inhibited cell growth and proliferation potential, reduced IL-6 secretion, cervical expression of IL-6R and induced apoptosis of HeLa cells in vitro. maslinic acid 9-22 interleukin 6 Homo sapiens 99-103 28599489-0 2017 Maslinic acid suppresses the growth of human gastric cells by inducing apoptosis via inhibition of the interleukin-6 mediated Janus kinase/signal transducer and activator of transcription 3 signaling pathway. maslinic acid 0-13 interleukin 6 Homo sapiens 103-116 28599489-7 2017 Maslinic acid treatment also resulted in the downregulation of phosphorylated-STAT3 and JAK2, and significantly inhibited the protein expression of IL-6. maslinic acid 0-13 interleukin 6 Homo sapiens 148-152 28599489-8 2017 Maslinic acid is able to inhibit MKN28 cell proliferation and the phosphorylation of STAT3 by downregulating the expression of IL-6. maslinic acid 0-13 interleukin 6 Homo sapiens 127-131 28599489-9 2017 These results suggest that maslinic acid suppresses the growth of MKN28 cells by inducing apoptosis via its inhibition of the IL-6/JAK/STAT3 signaling cascade. maslinic acid 27-40 interleukin 6 Homo sapiens 126-130