PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27149037-5 2016 Thus, maslinic acid derived N-[2beta,3beta-di-O-acetyl-17beta-amino-28-norolean-12-en-17-yl]phenylurea (45) gave best results showing EC50 = 0.9 muM (for A2780 ovarian cancer cells) with EC50 > 120 muM for fibroblasts (NIH 3T3) and triggered apoptosis while caspase-3 was not activated by this compound. maslinic acid 6-19 caspase 3 Homo sapiens 261-270 16988125-5 2006 Caspase-3 was activated in a dose-dependent manner after incubation for 24 h. The extract containing 200 micromol/L maslinic acid and 74 micromol/L oleanolic acid increased caspase-3-like activity to 6-fold that of control cells. maslinic acid 116-129 caspase 3 Homo sapiens 0-9 16988125-5 2006 Caspase-3 was activated in a dose-dependent manner after incubation for 24 h. The extract containing 200 micromol/L maslinic acid and 74 micromol/L oleanolic acid increased caspase-3-like activity to 6-fold that of control cells. maslinic acid 116-129 caspase 3 Homo sapiens 173-182 21279332-11 2011 Taken together, in ACC cells, maslinic acid induced an increase in [Ca(2+)](i), which evoked p38 MAPK phosphorylation, subsequently activated caspase-3 leading to apoptosis. maslinic acid 30-43 caspase 3 Homo sapiens 142-151 18298868-6 2008 In contrast, maslinic acid increased caspase-3-like activity at 10, 25 and 50 micromol/l by 3-, 3.5- and 5-fold over control cells, respectively. maslinic acid 13-26 caspase 3 Homo sapiens 37-46