PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12364628-2 2002 METHODS: Sixteen patients who were still active despite combination therapy with optimal doses of methotrexate (MTX 15-17.5 mg/week) and cyclosporin A (CsA 2.5-3.5 mg/day) received infliximab. Cyclosporine 137-150 IK cytokine Homo sapiens 152-157 10674906-2 2000 We report here 9 cases of neutropenic HLH, of which 8 were treated with cyclosporin (CSA, 2-6 mg/kg/day; continuous infusion, or 6 mg/kg/day; per os, for periods ranging from 9 days to >8 weeks) in the initial neutropenic phase during induction treatment using corticosteroids and etoposide. Cyclosporine 72-83 IK cytokine Homo sapiens 85-93 10232563-16 1999 In patients on NEO, the concentration of CsA 2 hr after dosing (C2) closely reflected AUC0-6 (r2 = 0.93), whereas there was a poorer correlation in patients on SIM (r2 = 0.73) CONCLUSIONS: Cmax and/or AUC0-6 may provide better markers than trough levels for monitoring CsA-based immune suppression after orthotopic liver transplantation. Cyclosporine 15-18 IK cytokine Homo sapiens 41-46 8939689-5 1996 Here we describe the synthesis of a novel CID, (CsA)2, that has two identical protein-binding surfaces derived from the immunosuppressant cyclosporin A (CsA). Cyclosporine 138-151 IK cytokine Homo sapiens 48-53 8939689-7 1996 RESULTS: (CsA)2 was synthesized in six synthetic steps and 30% overall yield from cyclosporin. Cyclosporine 82-93 IK cytokine Homo sapiens 10-15