PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17452893-6 2007 A larger than 10 mL/min 1.73 m decrease in glomerular filtration rate was observed in more patients on CsA than on MMF (73% vs. 29%, P=0.019). Cyclosporine 103-106 CD59 molecule (CD59 blood group) Homo sapiens 20-25 28457398-13 2017 A significant difference on MgS levels between patients on tacrolimus and cyclosporine was found only when considering GFR <45 mL/min/1.73 m2, in which patients on tacrolimus had significantly higher GFR than patients on cyclosporine, which may explain these results. Cyclosporine 74-86 CD59 molecule (CD59 blood group) Homo sapiens 133-138 28556421-11 2017 There was a significant increase in the frequency of contractions after ciclosporin, tacrolimus, azathioprine and sirolimus treatment compared with control animals (4.6 +- 0.3 cycles min-1 ). Cyclosporine 72-83 CD59 molecule (CD59 blood group) Homo sapiens 183-188 22797101-8 2012 Also, GFR was 79.8 +- 22.3 mL/min/1.73 m2 in the sirolimus group and 70.3 +- 23.6 mL/min/1.73 m2 in the cyclosporine group B (P = .04). Cyclosporine 104-116 CD59 molecule (CD59 blood group) Homo sapiens 85-90 10606886-6 1999 Flow cytometric analysis of the peripheral blood of this patient during remission after cyclosporine therapy revealed 1.7% of granulocytes to be deficient in CD59. Cyclosporine 88-100 CD59 molecule (CD59 blood group) Homo sapiens 158-162 17727303-15 2007 Treatment with ciclosporin should be limited to patients with a relatively normal renal function (GFR >60 mL/min/1.73m(2)) in view of its nephrotoxicity in patients with renal dysfunction. Cyclosporine 15-26 CD59 molecule (CD59 blood group) Homo sapiens 112-117 11907418-8 2002 During cyclosporine, glomerular filtration rate decreased from 98+/-9 ml/min/1.732 to 85+/-10 ml/min/1.732 (P<0.05), and ERPF decreased from 597+/-108 ml/min/1.732 to 438+/-84 ml/min/1.732 (P<0.01). Cyclosporine 7-19 CD59 molecule (CD59 blood group) Homo sapiens 73-78 11907418-8 2002 During cyclosporine, glomerular filtration rate decreased from 98+/-9 ml/min/1.732 to 85+/-10 ml/min/1.732 (P<0.05), and ERPF decreased from 597+/-108 ml/min/1.732 to 438+/-84 ml/min/1.732 (P<0.01). Cyclosporine 7-19 CD59 molecule (CD59 blood group) Homo sapiens 97-102 11907418-8 2002 During cyclosporine, glomerular filtration rate decreased from 98+/-9 ml/min/1.732 to 85+/-10 ml/min/1.732 (P<0.05), and ERPF decreased from 597+/-108 ml/min/1.732 to 438+/-84 ml/min/1.732 (P<0.01). Cyclosporine 7-19 CD59 molecule (CD59 blood group) Homo sapiens 97-102 11907418-8 2002 During cyclosporine, glomerular filtration rate decreased from 98+/-9 ml/min/1.732 to 85+/-10 ml/min/1.732 (P<0.05), and ERPF decreased from 597+/-108 ml/min/1.732 to 438+/-84 ml/min/1.732 (P<0.01). Cyclosporine 7-19 CD59 molecule (CD59 blood group) Homo sapiens 97-102 8190529-10 1994 Immunosuppressive treatment with cyclosporin therapy in combination with a minimal dose of alternate-day prednisone would then result in optimal post-transplant growth, particularly if the GFR remains above 50 mL/min/1.73 m2). Cyclosporine 33-44 CD59 molecule (CD59 blood group) Homo sapiens 213-218 7534714-4 1995 Flow-cytometric analysis revealed a normal expression of GPI-linked membrane proteins, including CD55, CD59, and CD16 on PMN in all patients treated with CyA, irrespective of response, except for one patient who had a small proportion of GPI-anchored membrane protein-negative cells before therapy. Cyclosporine 154-157 CD59 molecule (CD59 blood group) Homo sapiens 103-107 7870353-4 1994 After CsA withdrawal the GFR increased, median from 74 ml min-1 to 90 ml min-1, (P < 0.04). Cyclosporine 6-9 CD59 molecule (CD59 blood group) Homo sapiens 58-63 7870353-4 1994 After CsA withdrawal the GFR increased, median from 74 ml min-1 to 90 ml min-1, (P < 0.04). Cyclosporine 6-9 CD59 molecule (CD59 blood group) Homo sapiens 73-78 3300293-5 1987 In 23 patients receiving CyA in whom the serum creatinine concentration was less than 2.0 mg/dL, the mean DTPA clearance was 49.5 +/- 2.83 mL/min/1.73 m2. Cyclosporine 25-28 CD59 molecule (CD59 blood group) Homo sapiens 142-147 1942772-4 1991 The glomerular filtration rate and renal plasma flow were significantly depressed below normal values in transplant recipients given cyclosporine, averaging 35 +/- 8 and 325 +/- 94 ml/min/1.73 m2, respectively. Cyclosporine 133-145 CD59 molecule (CD59 blood group) Homo sapiens 184-189 2142040-3 1990 During treatment for 12 to 18 months, cyclosporin A caused significant reductions in the glomerular filtration rate (before drug withdrawal, cyclosporin 97 +/- 18 vs placebo 125 +/- 16 ml min-1 1.73-m-2, p less than 0.05), renal plasma flow (454 +/- 83 vs 536 +/- 70 ml min-1 1.73-m-2, p less than 0.05), and lithium clearance (17 +/- 3 vs 28 +/- 5 ml min-1 1.73-m-2, p less than 0.05). Cyclosporine 38-49 CD59 molecule (CD59 blood group) Homo sapiens 188-193 2142040-3 1990 During treatment for 12 to 18 months, cyclosporin A caused significant reductions in the glomerular filtration rate (before drug withdrawal, cyclosporin 97 +/- 18 vs placebo 125 +/- 16 ml min-1 1.73-m-2, p less than 0.05), renal plasma flow (454 +/- 83 vs 536 +/- 70 ml min-1 1.73-m-2, p less than 0.05), and lithium clearance (17 +/- 3 vs 28 +/- 5 ml min-1 1.73-m-2, p less than 0.05). Cyclosporine 38-49 CD59 molecule (CD59 blood group) Homo sapiens 270-275 2142040-3 1990 During treatment for 12 to 18 months, cyclosporin A caused significant reductions in the glomerular filtration rate (before drug withdrawal, cyclosporin 97 +/- 18 vs placebo 125 +/- 16 ml min-1 1.73-m-2, p less than 0.05), renal plasma flow (454 +/- 83 vs 536 +/- 70 ml min-1 1.73-m-2, p less than 0.05), and lithium clearance (17 +/- 3 vs 28 +/- 5 ml min-1 1.73-m-2, p less than 0.05). Cyclosporine 38-49 CD59 molecule (CD59 blood group) Homo sapiens 270-275 2142040-3 1990 During treatment for 12 to 18 months, cyclosporin A caused significant reductions in the glomerular filtration rate (before drug withdrawal, cyclosporin 97 +/- 18 vs placebo 125 +/- 16 ml min-1 1.73-m-2, p less than 0.05), renal plasma flow (454 +/- 83 vs 536 +/- 70 ml min-1 1.73-m-2, p less than 0.05), and lithium clearance (17 +/- 3 vs 28 +/- 5 ml min-1 1.73-m-2, p less than 0.05). Cyclosporine 38-51 CD59 molecule (CD59 blood group) Homo sapiens 188-193 2142040-3 1990 During treatment for 12 to 18 months, cyclosporin A caused significant reductions in the glomerular filtration rate (before drug withdrawal, cyclosporin 97 +/- 18 vs placebo 125 +/- 16 ml min-1 1.73-m-2, p less than 0.05), renal plasma flow (454 +/- 83 vs 536 +/- 70 ml min-1 1.73-m-2, p less than 0.05), and lithium clearance (17 +/- 3 vs 28 +/- 5 ml min-1 1.73-m-2, p less than 0.05). Cyclosporine 38-51 CD59 molecule (CD59 blood group) Homo sapiens 270-275 2142040-3 1990 During treatment for 12 to 18 months, cyclosporin A caused significant reductions in the glomerular filtration rate (before drug withdrawal, cyclosporin 97 +/- 18 vs placebo 125 +/- 16 ml min-1 1.73-m-2, p less than 0.05), renal plasma flow (454 +/- 83 vs 536 +/- 70 ml min-1 1.73-m-2, p less than 0.05), and lithium clearance (17 +/- 3 vs 28 +/- 5 ml min-1 1.73-m-2, p less than 0.05). Cyclosporine 38-51 CD59 molecule (CD59 blood group) Homo sapiens 270-275 3554640-4 1987 Clearance studies 6 weeks after Tx exhibited significantly lower rates in the CsA group: Cin = 47 +/- 16.5 versus 83 +/- 25 ml/min/1.73 sqm, CPAH = 271 +/- 110 versus 503 +/- 181 ml/min/1.73 sqm (P less than 0.001). Cyclosporine 78-81 CD59 molecule (CD59 blood group) Homo sapiens 127-132 3554640-4 1987 Clearance studies 6 weeks after Tx exhibited significantly lower rates in the CsA group: Cin = 47 +/- 16.5 versus 83 +/- 25 ml/min/1.73 sqm, CPAH = 271 +/- 110 versus 503 +/- 181 ml/min/1.73 sqm (P less than 0.001). Cyclosporine 78-81 CD59 molecule (CD59 blood group) Homo sapiens 182-187 2415587-5 1985 The fact that all the changes observed can be inhibited by low concentrations (I50 = 50 ng/ml) of cyclosporin A is further evidence that 1F5 is involved at an early stage of B cell activation. Cyclosporine 98-111 CD59 molecule (CD59 blood group) Homo sapiens 137-140