PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
14507967-7	2003	When cultured oligodendrocytes were exposed to staurosporine or cyclosporin A, drugs known to stimulate apoptosis in oligodendrocytes, those from Bax-/- mice but not from Bax+/+ or Bax+/- mice were resistant to the apoptotic death.	Cyclosporine	64-77	BCL2-associated X protein	Mus musculus	146-149	
14638906-9	2003	Apoptosis induced by CsA is associated with the translocation of Bax to the mitochondria and Bax antisense oligodeoxynucleotides protected from CsA-induced apoptosis.	Cyclosporine	144-147	BCL2-associated X protein	Mus musculus	93-96	
18230621-9	2008	These results, thus, argue for the existence of an alternative Bax/Bak-independent apoptotic mechanism that involves cyclosporine A-sensitive mitochondrial membrane permeability.	Cyclosporine	117-131	BCL2-associated X protein	Mus musculus	63-66	
14638906-9	2003	Apoptosis induced by CsA is associated with the translocation of Bax to the mitochondria and Bax antisense oligodeoxynucleotides protected from CsA-induced apoptosis.	Cyclosporine	21-24	BCL2-associated X protein	Mus musculus	65-68	
14638906-9	2003	Apoptosis induced by CsA is associated with the translocation of Bax to the mitochondria and Bax antisense oligodeoxynucleotides protected from CsA-induced apoptosis.	Cyclosporine	21-24	BCL2-associated X protein	Mus musculus	93-96	
24559268-11	2014	Increased apoptotic cell death and a high ratio of B cell leukaemia/lymphoma 2 (Bcl-2)-associated X protein (Bax) to Bcl-2 in CsA-treated mice were also significantly ameliorated by OA treatment.	Cyclosporine	126-129	BCL2-associated X protein	Mus musculus	109-112	
12123203-9	2002	The ratio between bax and bcl-2 protein increased significantly in the CsA group (5.3-fold), compared with the VH group.	Cyclosporine	71-74	BCL2-associated X protein	Mus musculus	18-21	
11254887-4	2001	In addition, the role of apoptosis inhibitors (Bcl-2 and Bcl-x) and the apoptosis inducer (Bax) in CsA induced-apoptosis was evaluated.	Cyclosporine	99-102	BCL2-associated X protein	Mus musculus	91-94	
11254887-5	2001	The expression of Bcl-2 and Bax proteins were high in LBC cells and following CsA treatment the expression of these proteins as well as Bcl-XL decreased.	Cyclosporine	78-81	BCL2-associated X protein	Mus musculus	28-31	
34565275-6	2021	CsA increased caspase-3 activity, Bax, TOS, MDA, TAS, and MPO levels, and the administration of DAPA with CsA significantly reduced this increase in levels (p < 0.001, p < 0.001, p < 0.001, p < 0.001, p < 0.001, and p < 0.001, respectively).	Cyclosporine	0-3	BCL2-associated X protein	Mus musculus	34-37	
32188225-6	2017	Compared with the BMF group, the CSA and flavone groups had significantly higher and expressions of caspase family proteins (all P<0.05) whereas the levels of Cyt C, PS, Ca2+, and expressions of Bak and Bax were reduced (all P<0.05).	Cyclosporine	33-36	BCL2-associated X protein	Mus musculus	203-206	
28957350-12	2017	CyA pretreatment and/or RIP3(-/-) mice decreased Bax/Bcl2 expression; however, it did lead to an overall change in the levels of AST, ALT and LDH or necrotic injury.	Cyclosporine	0-3	BCL2-associated X protein	Mus musculus	49-52	
27580845-6	2016	Treatment with CsA and FK506 also inhibited PAN-induced podocytes apoptosis, which was associated with the induction of Bcl-xL and inhibition of Bax, cleaved caspase 3, and cleaved PARP expression.	Cyclosporine	15-18	BCL2-associated X protein	Mus musculus	145-148