PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34854520-10	2022	Valosin-containing protein (VCP), a suppressor of cardiac hypertrophy via inhibiting mechanistic target of rapamycin (mTOR) signaling, was validated as a target of miR-339-5p.	mir-339-5p	164-174	mechanistic target of rapamycin kinase	Rattus norvegicus	85-116	
34854520-11	2022	MiR-339-5p suppressed VCP protein expression, leading to elevated phosphorylation of mTOR and ribosomal protein S6 kinase (S6K).	mir-339-5p	0-10	mechanistic target of rapamycin kinase	Rattus norvegicus	85-89	
34854520-12	2022	VCP depletion activated the mTOR/S6K cascade and could compromise the anti-hypertrophic effects of miR-339-5p inhibitor.	mir-339-5p	99-109	mechanistic target of rapamycin kinase	Rattus norvegicus	28-32	
34854520-13	2022	Additionally, the hypertrophic responses caused by miR-339-5p was alleviated in the presence of mTOR inhibitor rapamycin.	mir-339-5p	51-61	mechanistic target of rapamycin kinase	Rattus norvegicus	96-100	
34854520-14	2022	In conclusion, our research revealed that miR-339-5p promoted ISO-induced cardiomyocyte hypertrophy by targeting VCP to activate the mTOR signaling, suggesting a promising therapeutic intervention by interfering miR-339-5p.	mir-339-5p	42-52	mechanistic target of rapamycin kinase	Rattus norvegicus	133-137	
34854520-10	2022	Valosin-containing protein (VCP), a suppressor of cardiac hypertrophy via inhibiting mechanistic target of rapamycin (mTOR) signaling, was validated as a target of miR-339-5p.	mir-339-5p	164-174	mechanistic target of rapamycin kinase	Rattus norvegicus	118-122