PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35118192-0	2022	Narciclasine targets STAT3 via distinct mechanisms in tamoxifen-resistant breast cancer cells.	narciclasine	0-12	signal transducer and activator of transcription 3	Homo sapiens	21-26	
35118192-9	2022	Our findings successfully highlight the STAT3 as the direct therapeutic target of Nar in ER-positive breast cancer cells, especially, Nar leaded STAT3 degradation as a promising strategy for the tamoxifen-resistant breast cancer treatment.	narciclasine	82-85	signal transducer and activator of transcription 3	Homo sapiens	40-45	
35118192-9	2022	Our findings successfully highlight the STAT3 as the direct therapeutic target of Nar in ER-positive breast cancer cells, especially, Nar leaded STAT3 degradation as a promising strategy for the tamoxifen-resistant breast cancer treatment.	narciclasine	82-85	signal transducer and activator of transcription 3	Homo sapiens	145-150	
35118192-9	2022	Our findings successfully highlight the STAT3 as the direct therapeutic target of Nar in ER-positive breast cancer cells, especially, Nar leaded STAT3 degradation as a promising strategy for the tamoxifen-resistant breast cancer treatment.	narciclasine	134-137	signal transducer and activator of transcription 3	Homo sapiens	40-45	
35118192-9	2022	Our findings successfully highlight the STAT3 as the direct therapeutic target of Nar in ER-positive breast cancer cells, especially, Nar leaded STAT3 degradation as a promising strategy for the tamoxifen-resistant breast cancer treatment.	narciclasine	134-137	signal transducer and activator of transcription 3	Homo sapiens	145-150	
35118192-6	2022	In addition, Nar could specifically degrade total STAT3 via the proteasome pathway in MCF-7/TR (tamoxifen-resistant MCF-7) cells.	narciclasine	13-16	signal transducer and activator of transcription 3	Homo sapiens	50-55	
35118192-8	2022	Meanwhile, Nar-loaded nanoparticles could markedly decrease the protein levels of STAT3 in tumors, resulting in significantly increased MCF-7/TR xenograft tumor regression without obvious toxicity.	narciclasine	11-14	signal transducer and activator of transcription 3	Homo sapiens	82-87