PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26177745-0	2015	Concentration-dependent differential effects of an epothilone analog on cell cycle and p53 signaling.	Epothilones	51-61	tumor protein p53	Homo sapiens	87-90	
26177745-4	2015	In the present study, we demonstrated that UTD1, a genetically engineered epothilone analog and a new microtubule inhibitor, activated p53 as a transcription factor at low concentrations demonstrated by its enhanced transcriptional activity and accumulation of p21, which led to cell cycle arrest.	Epothilones	74-84	tumor protein p53	Homo sapiens	135-138	
26177745-6	2015	These observations indicate that the epothilone analog has differential effects on intracellular signaling and implies that p53 plays different roles in cells exposed to different concentrations of the anticancer agent.	Epothilones	37-47	tumor protein p53	Homo sapiens	124-127	
21559393-0	2011	Molecular mode of action and role of TP53 in the sensitivity to the novel epothilone sagopilone (ZK-EPO) in A549 non-small cell lung cancer cells.	Epothilones	74-84	tumor protein p53	Homo sapiens	37-41