PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34221003-10	2021	In the LPS-induced HT22 cells, hyperoside promotes cell survival; alleviates the level of IL-1beta, IL-6, IL-8, TNF-alpha, ROS, MDA, Bax, and caspase-3; and increases the expression of CAT, SOD, GSH, Bcl-2, BDNF, TrkB, and NGF.	hyperoside	31-41	interleukin 6	Mus musculus	100-104	
33192501-8	2020	Hyperoside treatment also reduced the levels of MDA, TNF-alpha, and IL-6 and increased the activity of SOD.	hyperoside	0-10	interleukin 6	Mus musculus	68-72	
26526086-4	2015	In this study, HP not only significantly attenuated inflammation in C57BL/6J mice with acute liver injury (ALI), but also reduced the expression of TNF-alpha and IL-6 in lipopolysaccharide (LPS)-induced RAW264.7 cells.	hyperoside	15-17	interleukin 6	Mus musculus	162-166	
26526086-7	2015	More importantly, over-expression of PPAR-gamma had an opposite effect on the expression of TNF-alpha and IL-6 in LPS-induced RAW264.7 cells after treatment with HP.	hyperoside	162-164	interleukin 6	Mus musculus	106-110	
27041460-11	2016	Furthermore, hyperoside decreased LPS-stimulated production of TNF-alpha, IL-6, IL-1 and MMP-9 in the cells.	hyperoside	13-23	interleukin 6	Mus musculus	74-78	
21213407-3	2011	In this study, hyperoside was shown to exert an anti-inflammatory action through suppressed production of tumor necrosis factor, interleukin-6, and nitric oxide in lipopolysaccharide-stimulated mouse peritoneal macrophages.	hyperoside	15-25	interleukin 6	Mus musculus	129-142	
21213407-4	2011	The maximal inhibition rate of tumor necrosis factor-alpha, interleukin-6, and nitric oxide production by 5 muM hyperoside was 32.31 +- 2.8%, 41.31 +- 3.1%, and 30.31 +- 4.1%, respectively.	hyperoside	112-122	interleukin 6	Mus musculus	60-73