PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18996370-4	2009	Microarray analysis using a tetracycline-inducible LMX1B expression system in HeLa cells revealed that a subset of NF-kappaB target genes, including IL-6 and IL-8, are upregulated in LMX1B-expressing cells.	Tetracycline	28-40	C-X-C motif chemokine ligand 8	Homo sapiens	158-162	
19258275-2	2009	In this study, we examined the effects of tetracycline (TET) and two of its derivatives, doxycycline (DOX) and minocycline (MIN), on the production of interleukin-8 (IL-8) elicited by the activation of protease-activated receptor 2 (PAR2) in normal human epidermal keratinocytes (NHEK).	Tetracycline	42-54	C-X-C motif chemokine ligand 8	Homo sapiens	151-164	
19258275-2	2009	In this study, we examined the effects of tetracycline (TET) and two of its derivatives, doxycycline (DOX) and minocycline (MIN), on the production of interleukin-8 (IL-8) elicited by the activation of protease-activated receptor 2 (PAR2) in normal human epidermal keratinocytes (NHEK).	Tetracycline	42-54	C-X-C motif chemokine ligand 8	Homo sapiens	166-170	
18341570-0	2008	Tetracycline suppresses ATP gamma S-induced CXCL8 and CXCL1 production by the human dermal microvascular endothelial cell-1 (HMEC-1) cell line and primary human dermal microvascular endothelial cells.	Tetracycline	0-12	C-X-C motif chemokine ligand 8	Homo sapiens	44-49	
10624772-6	1999	Furthermore, IL-8, Gro and MCP-1 concentrations decreased between 24 and 72 h. Immunocytochemistry indicated expression of IL-8 by pleural mesothelial cells 24 h, but not 72 h, following TCN administration.	Tetracycline	187-190	C-X-C motif chemokine ligand 8	Homo sapiens	13-17	
10624772-6	1999	Furthermore, IL-8, Gro and MCP-1 concentrations decreased between 24 and 72 h. Immunocytochemistry indicated expression of IL-8 by pleural mesothelial cells 24 h, but not 72 h, following TCN administration.	Tetracycline	187-190	C-X-C motif chemokine ligand 8	Homo sapiens	123-127	
10624772-7	1999	The data suggest that local elaboration of interleukin-8 and growth-related protein, in part of mesothelial origin, may influence neutrophil recruitment in tetracycline-induced pleuritis.	Tetracycline	156-168	C-X-C motif chemokine ligand 8	Homo sapiens	43-56	
8503562-0	1993	Changes in cell population and tumor necrosis factor, interleukin-6, and interleukin-8 in malignant pleural effusions after treatment with intrapleural tetracycline.	Tetracycline	152-164	C-X-C motif chemokine ligand 8	Homo sapiens	73-86	
8503562-8	1993	The results suggest that TC intrapleural injection induces the release of cytokines (IL-6 and TNF), which are markers of an inflammatory response, and releases IL-8, which attracts neutrophils into the pleural space, which may be the mechanism of the sclerosing effect of TC.	Tetracycline	25-27	C-X-C motif chemokine ligand 8	Homo sapiens	160-164