PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30940721-1 2019 In an interim analysis, the targeted PARP inhibitor rucaparib showed encouraging signs of disease control when used as a maintenance therapy for patients with platinum-sensitive advanced pancreatic cancer and a pathogenic mutation in BRCA1, BRCA2, or PALB2. rucaparib 52-61 partner and localizer of BRCA2 Homo sapiens 251-256 33970687-0 2021 Phase II Study of Maintenance Rucaparib in Patients With Platinum-Sensitive Advanced Pancreatic Cancer and a Pathogenic Germline or Somatic Variant in BRCA1, BRCA2, or PALB2. rucaparib 30-39 partner and localizer of BRCA2 Homo sapiens 168-173 33970687-14 2021 CONCLUSION: Maintenance rucaparib is a safe and effective therapy for platinum-sensitive, advanced PC with a PV in BRCA1, BRCA2, or PALB2. rucaparib 24-33 partner and localizer of BRCA2 Homo sapiens 132-137 35205643-6 2022 Selective poly (ADP-ribose) polymerase (PARP) inhibitors such as Niraparib, Olaparib, Talazoparib, Rucaparib, and Veliparib are now approved for several cancers with loss of high-fidelity double-strand break homologous recombination (HR), namely those with deleterious mutations to BRCA1/2, PALB2, and other functionally related genes. rucaparib 99-108 partner and localizer of BRCA2 Homo sapiens 291-296