PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33155655-8	2020	In bone defect mice, ICA inhibited the expressions of NF-kappaB and HIF-2alpha.	icariin	21-24	endothelial PAS domain protein 1	Mus musculus	68-78	
33155655-0	2020	Icariin inhibits the inflammation through down-regulating NF-kappaB/HIF-2alpha signal pathways in chondrocytes.	icariin	0-7	endothelial PAS domain protein 1	Mus musculus	68-78	
33155655-6	2020	The effect of ICA on HIF-2alpha is unclear by now.	icariin	14-17	endothelial PAS domain protein 1	Mus musculus	21-31	
33155655-10	2020	Furthermore, ICA inhibited the nucleus transfer of NF-kappaB and the expressions of MMP9 and ADAMTS5, two key targets of NF-kappaB/HIF-2alpha signal pathway.	icariin	13-16	endothelial PAS domain protein 1	Mus musculus	131-141	
33155655-11	2020	Taken together, this study demonstrated that ICA may increase the vitality of chondrocytes by suppressing the inflammatory injury through the inhibition on NF-kappaB/HIF-2alpha signaling pathway.	icariin	45-48	endothelial PAS domain protein 1	Mus musculus	166-176