PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20686223-2 2010 We found that this icariin derivative inhibits tumor necrosis factor-alpha (TNF-alpha) production, inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) mRNA expression, and protein expression in lipopolysaccharide (LPS) stimulated RAW264.7 macrophages. icariin 19-26 prostaglandin-endoperoxide synthase 2 Mus musculus 142-158 20686223-2 2010 We found that this icariin derivative inhibits tumor necrosis factor-alpha (TNF-alpha) production, inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) mRNA expression, and protein expression in lipopolysaccharide (LPS) stimulated RAW264.7 macrophages. icariin 19-26 prostaglandin-endoperoxide synthase 2 Mus musculus 160-165 30978648-10 2019 Icariin treatment prominently mitigated the protein expression of proinflammatory factors like nuclear factor-kappaB, cyclooxygenase-2, interleukin 1-beta and prooxidative enzyme (NADPH oxidase-4), and it increased the protein expression of antioxidative enzymes (superoxide dismutase and catalase). icariin 0-7 prostaglandin-endoperoxide synthase 2 Mus musculus 118-134