PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26221250-9 2015 Furthermore, the downstream transcription factors of MAPK pathway, Elk1, Stat3, c-Myc and Fos, are also monitored by RT-PCR, and our results show that among them, Elk1 and c-Myc are significantly upregulated after ICA treatment. icariin 214-217 ETS transcription factor ELK1 Rattus norvegicus 163-167 26221250-10 2015 Taken together, our results demonstrate that ICA promotes the proliferation of rat BMSCs through activating ERK and p38 MAPK signaling which further leads to upregulation of their downstream transcription factors Elk1 and c-Myc. icariin 45-48 ETS transcription factor ELK1 Rattus norvegicus 213-217