PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32124960-13	2020	Overall, the present study provided evidence that ICA sensitized tumor cells to TRAIL-induced apoptosis via ROS-, ERK- and CHOP-mediated upregulation of DR5 and DR4.	icariin	50-53	DNA damage inducible transcript 3	Homo sapiens	123-127	
26049256-4	2015	Furthermore, ICA treatment increased the expression of ERS-related molecules (p-PERK, ATF6, GRP78, p-eIF2alpha, and CHOP), up-regulated the apoptosis-related protein PUMA and down-regulated the anti-apoptosis-related protein Bcl2.	icariin	13-16	DNA damage inducible transcript 3	Homo sapiens	116-120	
26049256-6	2015	Additionally, ICA inhibited the growth of human lung adenocarcinoma A549 cell xenografts by increasing the expression of ERS-related molecules (p-PERK and CHOP), up-regulating PUMA, and down-regulating Bcl2.	icariin	14-17	DNA damage inducible transcript 3	Homo sapiens	155-159